A paper published on April 20, 2012 testing a coronavirus vaccine in mice, concludes by warning of “proceeding to application of a SARS-CoV vaccine in humans” because of the reaction the mice experience upon challenged with the virus post vaccination. Many mice died because of immune priming or antibody dependent enhancement (ADE), where the vaccine induced an immune response that enhanced the bodies reaction upon rechallenge, sending the animals into a cytokine storm.
