On January 12, 2022, the European Medicines Agency (EMA) warns that frequent boosters every 4 months could adversely affect the immune system and may not be feasible. Boosters “can be done once, or maybe twice, but it’s not something that we can think should be repeated constantly,” said Marco Cavaleri, the EMA head

The narrative is now being steered towards “following the blueprint set out by influenza vaccination strategies”.  A pre-season flu shots will align with a COVID-19 preseason shot.

The U.K. has said that boosters are providing good levels of protection and there is no need for a second booster shot at the moment.  Booster less effective against mild illness for Omicron.

Back in March 2021 Australian TGA’s Access Consortium was already looking at changing the mRNA code during the pandemic, in a provisionally registered vaccine, and compare that to what is done with seasonal influenza – yet they are completely different technologies.