Following is a small selection of information on the power of vitamin D – the health and immune benefits and it’s mode of action. Included is information on Vitamin D and COVID-19.
Vitamin D levels correlate strongly with SARS-CoV-2 infection severity,
with a theoretical point of zero mortality at approximately 50 ng/mL D3 – REF
Vitamin D administration results in a decreased risk of death and ICU admission.– REF
Overview on Vitamin D
This one hour presentation by Dr Michael F. Holick – a compelling overview of the power of vitamin D.
As temperature goes down (so too does the sunshine)
An interesting look at a time-laps video below showing as the US temperature drops (LEFT) the COVID-19 cases seem to follow along to some degree. When temperature decreases the tendency to stay outside reduces as well as the availability of sunshine hours decreases.
Dr Horick writes “when the angle of the sunlight (zenith angle) reaching the Earth’s surface is very oblique (ie, early morning, late afternoon, and winter), sunlight must pass through more ozone, which efficiently absorbs the previtamin D3-producing UVB photons, and thus very few, if any, reach the earth’s surface. Because the zenith angle is dependent on time of day, season of the year, and latitude, those factors have a dramatic effect on the cutaneous [skin] production of vitamin D3“
Dr Joe Prendergast & and Dr Liz Lipski on Vitamin D
Vitamin D is really a hormone. The whole immune system would become measurably stronger by a factor of 3-5 times, probalby better than any vaccines, for any virus. – Dr Prendergast – circa 2007
“57% of us a vitamin D deficient”, 92% of people with high pigmented skin are vitamin D deficient, making one more susceptible to colds and flu, amongst other things – Dr Liz Lipski 2008
How our body makes vitamin D – EXCERPT
COVID-19 and Vitamin D
2023
Novmeber 30, 2023 – The Highwire Ep 348: The 500 Billion Dollar Man – Dr Eric Nepute – WATCH, FULL
- Sued by the government for $508 Billion for recommending Vitamin D and Zinc for COVID-19 – he stood his ground and didn’t cave. Listen to his story
November 12, 2023 – Dr John Campbell: The Great Biological Reset – interview w/ Professor David Anderson – WATCH, BACKUP
- BOOK: Vitamin D3 and the Great Biology Reset – A journey from global D-deficiency and Lab-leaked viruses, to Nuclear Vaccines from the Gates of Hell- by Prof David Coussmaker Anderson w/ Dr David Stuart Grimes – WEBSITE, (download digital edition for free)
November 2, 2023 – Dr Ian Brighthope Substack: Vitamin D supplementation for optimum levels by Dr John Piesse – READ
September 27, 2023 – FLCCC Stories: Adess Singh Requested That a Campaign To Boost the Vitamin D Levels of the People of Punjab Be Undertaken Right Away – WATCH, CREDIT
May 15, 2023 – Dr John Campbell: Vitamin D doses – reasearch shows we are likely under dosed – WATCH
- January 4, 2019 – The Journal of Steroid Biochemistry and Molecular Biology: Daily oral dosing of vitamin D3 using 5000 TO 50,000 international units a day in long-term hospitalized patients: Insights from a seven year experience – McCullough et al – READ
February 9, 2023 – The Highwire Ep 306: NEW STUDY SHOWS MASKS DON’T WORK AGAINST ILLNESS, BUT WHAT DOES? – also more studies now show both vitamin D and exercise as cheap, empowering and extremely effective strategies against COVID – WATCH, FULL
February 2, 2023 – Dr John Campbell: Vitamin D, now conclusive – WATCH, STUDY
January 16, 2023 – Pharmaceuticals (Basel): Protective Effect of Vitamin D Supplementation on COVID-19-Related Intensive Care Hospitalization and Mortality: Definitive Evidence from Meta-Analysis and Trial Sequential Analysis [TSA] by Argano et al- READ, The Highwire – WATCH
- “We searched four databases on 20 September 2022. Two reviewers screened the randomized clinical trials (RCTs) and assessed the risk of bias, independently and in duplicate. The pre-specified outcomes of interest were mortality and ICU admission. …only five RCTs were found to be suitable for our analysis.” [no money to be made from Vitamin D research!]
- Vitamin D administration results in a decreased risk of death and ICU admission
- The results of the meta-analyses and respective TSAs suggest a definitive association between the protective role of vitamin D and ICU hospitalization.
2022
November 11, 2022 – Gateway Pundit: “I Humbly Risk It All Because I Know God Is In Control” – Dr. Eric Nepute told people to take vitamin D and zinc and the government is suing him for doing so – READ, TGP’s Joe Hoft Interviews Dr. Eric Nepute, the First Person Charged Under COVID False Claims Law – WATCH
October 25, 2022 – Annals of Internal Medicine: Vitamin D Deficiency Increases Mortality Risk in the UK Biobank – A Nonlinear Mendelian Randomization Study by Sutherland et al – READ
- “Our study supports a causal relationship between vitamin D deficiency and mortality.”
October 11, 2021 – Nutrients: COVID-19 Mortality Risk Correlates Inversely with Vitamin D3 Status, and a Mortality Rate Close to Zero Could Theoretically Be Achieved at 50 ng/mL 25(OH)D3: Results of a Systematic Review and Meta-Analysis – Borsche et al – READ, CREDIT
- “Much research shows that blood calcidiol (25(OH)D3) levels correlate strongly with SARS-CoV-2 infection severity.
- Regression suggested a theoretical point of zero mortality at approximately 50 ng/mL D3.
- “The datasets provide strong evidence that low D3 is a predictor rather than just a side effect of the infection. Despite ongoing vaccinations, we recommend raising serum 25(OH)D levels to above 50 ng/mL to prevent or mitigate new outbreaks due to escape mutations or decreasing antibody activity.”
September 26, 2022 – Dr Simon substack: Why Vitamin D is essential for a better Quality of Life – causal-loop diagrams to understand the metabolic pathways of vitamin D – READ
July 22, 2022 – Dr Brad Stanfield: When Exactly You Must Have a Vitamin D Test – WATCH
June 3, 2022 – Frontline Flash™ Daily Dose: ‘Why Is No One Talking About Vitamin D?’ with Dr. Peterson Pierre – The vitamin D group in the RCT of frontline workers had 4 x lower infection of COVID-19 – WATCH, ARTICLE
Published June 2022 – Archives of Medical Research: Efficacy and Safety of Vitamin D Supplementation to Prevent COVID-19 in Frontline Healthcare Workers. A Randomized Clinical Trial – Villasis-Keever et al – HERE
May 24, 2022 – Epoch Times: COVID-19 Is Treatable and Preventable With Vitamin D: Dr. Robert Malone – READ, WATCH
There are virtually no deaths from this disease [COVID-19] in people who have vitamin D levels in their blood above 50ng/mL [nanograms per millilitre].
Dr Robert Malone
May 8, 2022 – Dr Malone Substack: Preventable Deaths and D3 – The Ugly History of Vitamin D3 and Fauci’s pro-Vaccine Bias – READ
April 26, 2022 – Epoch Times: Vitamin D Supplementation Is Effective in Preventing COVID-19, Study Suggests – READ
April 11, 2022 – Archives of Medical Research: Efficacy and Safety of Vitamin D Supplementation to Prevent COVID-19 in Frontline Healthcare Workers. A Randomized Clinical Trial – Villasis-Keever et al – READ
April 7, 2022 – Dr John Campbell – Vitamin D Supplements for Prevention of Covid-19 or other Acute Respiratory Infections – WATCH
March 21, 2022 – Zdr Varst | Slovenian Journal of Public Health: COVID-19 and Vitamin D- a Systematic Review – Jordan et al – READ
- “Vitamin D supplementation might play an important role in protecting from acute respiratory infections like the SARS CoV2, and in high-risk individuals with COVID 19 from progressing to critical clinical condition and reducing mortality.”
February 17, 2022 – Orthomolecular: It’s Official: Vitamin D Reduces the Incidence of Autoimmunity – And a brief review of the growing body of knowledge of vitamin D – READ
January 9, 2022 – Orthomolecular Medicine News: Top Vitamin D Papers in 2021
Benefits ignored at a time they are most needed – READ
2021
December 31, 2021 – Evidence for Vitamin D and COVID outcomes (Gruff Davies, Linda Benskin & Bret Weinstein) – WATCH
December 22, 2021 – Paper: Vitamin D Status and SARS-CoV-2 Infection and COVID-19 Clinical Outcomes – READ
December 20, 2021 – There has been ZERO deaths from vitamins – READ
December 5, 2021 – CCCA: Vitamin D3 and COVID-19: A Brief for Family Physicians in Patients by Dr. Kanji Nakatsu, Ph.D. and Dr. Niel Karrow, Ph.D. – READ, PDF
October 14, 2021 – Nutrients: COVID-19 Mortality Risk Correlates Inversely with Vitamin D3 Status, and a Mortality Rate Close to Zero Could Theoretically Be Achieved at 50 ng/mL 25(OH)D3: Results of a Systematic Review and Meta-Analysis by Borsche et al – READ
- Regression suggested a theoretical point of zero mortality at approximately 50 ng/mL vitamin D3
August 13, 2021 – According to this new study, 84.4% of COVID-19 patients investigated had a vitamin D deficiency – TWEET, READ
May 18, 2021 – What’s Up Canada | Doctor Talks Part 6: Linda M. Rapson MD: Outpatient Treatment, “Host Resistance” with vitamin D – WATCH
March 15, 2021 – Wiener klinische Wochenschrift: Strong correlation between prevalence of severe vitamin D deficiency and population mortality rate from COVID-19 in Europe – Pugach et al – READ
- “The authors recommend universal screening for vitamin D deficiency, and further investigation of Vitamin D supplementation in randomized control studies, which may lead to possible treatment or prevention of COVID-19”
January 15, 2021 – Orthomolecular Medicine News: A Health Crisis Exposed by the COVID Pandemic- understanding the immune system – READ
January 10, 2021 – Orthomolecular Medicine News: Top 25 Vitamin D Publications in 2020 – READ
January 3, 2021 – MedCram: If You Get COVID 19: Optimize Immune System (Vitamin D, Monoclonal Antibodies, NAC, Quercetin etc.) – Professor Roger Seheult, MD gives practical strategies for combatting COVID-19 – WATCH, ARCHIVE
2020
December 22, 2020 – Gent Side: More than 130 experts have signed an open letter urging Boris Johnson to incorporate Vitamin D as part of the coronavirus strategy – READ
- The letter was sent to Boris Johnson and health Secretary Mike Hancock on Monday the 21st of December, advising that healthy adults should increase their daily vitamin D intake to 2,000 – 4000 international units (IU) during the pandemic.
December 17, 2020 – Public Health England | Scientific Advisory Committee on Nutrition (SACN) – NICE guideline: COVID-19 rapid guideline: vitamin D – PDF, ARCHIVE, READ
- “They stressed that everyone should consider taking a supplement containing 10 micrograms (400 units) of vitamin D daily between October and early March, when people in the UK do not make enough vitamin D from sunlight.” [Low dose!]
December 17, 2020 – National Institute for Health and Care Excellence (NICE UK) [NG187]: Vitamin D for COVID-19- [A] Evidence reviews for the use of vitamin D supplementation as prevention of COVID-19 – READ, ARCHIVE, PDF
- These evidence reviews were developed by Centre for Guidelines Methods and Economics Team
- This review aims to assess if vitamin D supplementation can prevent SARS CoV2 infection and subsequent COVID-19. It has been hypothesised that vitamin D is involved in the body’s immune response and could mitigate the inflammatory response.
- “No evidence relevant to the protocol was found for this question”
December 17, 2020 – Frontiers in Pharmacology: COVID-19 Disease and Vitamin D: A Mini-Review – Boulkrane et al – READ
- “Vitamin D is well-known to play a significant role in maintaining the immune health of an individual.” [SERIOUSLY, why not give it to the at risk then as a precautionary measure?]
- “Moreover, it induces antimicrobial peptide expression that can decrease viral replication and regulate the levels of pro-inflammatory/anti-inflammatory cytokines.”
- “We suggest that supplementation of subjects at high risk of COVID-19 with vitamin D (1.000 to 3.000 IU)…”[Too low for high risk?]
- “To verify this proposal, double-blind placebo-controlled trials and large-scale intervention and prevention studies using vitamin D3 are needed.” [Volunteers anyone!!!!]
November 27, 2020 – Nutrients: Vitamin D Insufficiency May Account for Almost Nine of Ten COVID-19 Deaths: Time to Act. Comment on: “Vitamin D Deficiency and Outcome of COVID-19 Patients – Brenner & Schottker – READ
- “Evidence from observational studies is accumulating, suggesting that the majority of deaths due to SARS-CoV-2 infections are statistically attributable to vitamin D insufficiency and could potentially be prevented by vitamin D supplementation
November 7, 2020 – The UK Telegraph: Vitamin D to be delivered to millions of vulnerable people to help protect them from Covid – Ministers draw up plans for four-month supplies to go to care home residents and clinically extremely vulnerable people in England – READ
October 16, 2020 – Daily Mail: Now Matt Hancock [UKs Health Secretary] says you SHOULD take vitamin D to boost your overall health amid mounting evidence it can protect against Covid-19 – U-turned on previous comments it has ‘no impact’ on Covid-19 – READ
- The about face “comes after scientists and MPs lambasted Mr Hancock for ‘ignoring’ the increasing number of studies which show vitamin D is linked with better Covid-19 outcomes. Several studies have shown people with a vitamin D deficiency, which is common in Britain, are more likely to catch the coronavirus, get seriously ill or die.”
- A row on the benefits of vitamin D came to a head two weeks ago when Matt Hancock wrongly told the House of Commons in September that a Government-funded ‘trial’ investigating it showed it did not ‘appear to have any impact’.
October 1, 2020 – Daily Mail: Since the Covid-19 epidemic started multiple studies have repeatedly shown a link to Vitamin D deficiency yet when Matt Hancock was asked about it he WRONGLY said a British study had found the opposite. Is he ignorant or incompetent? – READ
September 21, 2020 – UK House of Commons: UK Health Secretary Matt Hancock says trials of Vitamin D against COVID-19 are negative – WATCH, CREDIT, does an about face within a month.
December 23, 2020 – Orthomolecular Medicine News: Do the Math: “MATH+” Saves Lives – READ
September 17, 2020 – The Highwire: FAUCI TOUTS VITAMINS FOR COVID?! – WATCH
September 14, 2020 – Dr Shiva explains the mode of action of Vitamin D – WATCH
September 14, 2020 – Best Life: The 2 Vitamins Dr. Fauci Says You Should Take to Boost Immunity – Vitamin C & D – READ
September 12, 2020 – Insider: Fauci says that he takes vitamin D and C supplements and that they can lessen ‘your susceptibility to infection’ – READ
September 12, 2020 – Interview with Actress Jennifer Garner – WATCH, The supplement Dr. Fauci takes to help keep his immune system healthy – ARTICLE, The Highwire – WATCH
“If you are deficient in vitamin D, that does have an impact on your susceptibility to infection. So I would not mind recommending, and I do it myself taking vitamin D supplements,”
September 1, 2020 – Tiffany Haddish interviews Dr. Fauci about COVID-19 – WATCH
- “Fauci said in clinical studies most “so-called” immune-boosting supplements didn’t really help people unless they had some sort of a deficiency. In fact, a lot of these herbs “either do nothing, or, if you take too much of them, they harm you,””
- 2 days later paper shows Vit D deficiency increases risk of COVID-19 – READ
September 8, 2020 – Uni Chicago News: Vitamin D deficiency may raise risk of getting COVID-19, study finds – READ
June 29, 2020 – NICE UK: COVID-19 rapid evidence summary: vitamin D for COVID-19 – Evidence summary [ES28] – ARCHIVE
June 18, 2020 – The Royal Society | preprint: Vitamin D and COVID-19: This rapid review of the science of Vitamin D and COVID-19 from the Royal Society is provided to assist in the understanding of COVID-19. – READ
June 9, 2020 – Orthomolecular Medicine News: The role of vitamin D in reducing risk of COVID-19: a brief survey of the literature – READ
April 28, 2020 – MeRxiv pre print: Vitamin D insufficiency is prevalent in severe COVID-19 – Lau et al – READ
April 2, 2020 – MDPI | Nutrients: Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths – Grant et al – READ
March 29, 2020 – Dr Shiva Ayyadurai, PhD: How Vitamin D Destroys FOR YOU. A Molecular Systems Understanding. – WATCH
The virus is not what actually kills you. It is the over reaction of a weakened and dysfunctional immune system.”
Dr Shiva
- Vitamin D has many modes of action. When it comes to acute respiratory infections vitamin D supports the creation of cathelicidins, which are anti-microbial peptides (AMPs) – which destroy viruses by attacking their membranes – Dr Shiva explains this mode of action of the vitamin D
- Macrophages (primary white blood cells) are part of your innate immune system. There are two types of macrophages – M1 – Pro-inflammatory which support anti-microbial properties and M2 Anti-inflammatory which supports tissue repair
- March 18, 2019 – Nature: Cathelicidins PMAP-36, LL-37 and CATH-2 are similar peptides with different modes of action by Scheenstra et al – READ
- “…almost all cathelicidins show, in simple media, direct antimicrobial activity against many different bacteria, viruses, fungi, and parasites.”
March 23, 2020 – Fox News – Former CDC Chief Dr. Tom Frieden: Coronavirus infection risk may be reduced by Vitamin D – WATCH
March 23, 2020 – Dr Shiva sends letter to President Trump with science-based immune boost protocol, with Vitamin C & D being critical – TIMELINE, LETTER
February 11, 2020 – Immune Network: Vitamin D-Cathelicidin Axis: at the Crossroads between Protective Immunity and Pathological Inflammation during Infection by Chung et al – READ, Context see Dr Shiva’s presentation March 2020 above.
- “we discuss recent findings that demonstrate how the vitamin D-cathelicidin pathway regulates autophagy machinery, protective immune defenses, and inflammation, and contributes to immune cooperation between innate and adaptive immunity”
Pre-pandemic
2018
October 1, 2018 – Orthomolecular Medicine News – Vitamin D acceptance delayed by Big Pharma following the Disinformation Playbook – READ
June 2018 – Journal Steroid Biochemistry and Molecular Biology: In vivo response of the human epigenome to vitamin D: A Proof-of-principle study – Carlberg et al – READ
2017
February 13, 2017 – Orthomolecular Medicine News – The Top 18 Vitamin D Papers in 2015-2016 – READ
2016
April 22, 2016 – Biogena Academy Vienna: The D-Lightful Vitamin for Health – presentation by Dr. Michael F. Holick, Boston University Medical Center – Important information and facts about the vitamin D – WATCH
- [From the comments under this video] “I am a 66 year old obese type 2 diabetic who was vitamin D deficient, my doctor put me on 1000 units a day and I was still deficient I went to 5000 units a day and I was still deficient I then went to 10,000 units a day and I am just within the normal range….You have opened my eyes to the importance of vit D supplementation!”
2014
December 9, 2014 – Uni California TV: Vitamin D for Public Health: Integrating Sunshine, Supplements and Measurements for Optimal Health – presentation by Michael F. Holick, PhD MD, Boston University Medical Center – WATCH, SOURCED
2013
January 17, 2013 – Orthomolecular Medicine News: Vitamin D is Now the Most Popular Vitamin – READ
2008
March 2, 2008 – Dr Liz Lipski – Essential Information About Vitamin D – WATCH
- Mental institution patients were supplemented with vitamin D, as they were discovered to be deficient. The year a flu epidemic went through that hospital, these supplemented patients avoided getting sick! Vitamin D has anti-viral properties – EXCERPT
- The mechanism with which our body makes vitamin D from sunlight exposure: The skill cells make Cholecalciferol (Vitamin D3) from sunlight, this then goes to our liver to make 25-dihydroxyvitamin D3, which our kidneys then converted this to the active form of vitamin D, that’s actually a hormone. Optimal kidney function is essential. – EXCERPT
- Check your vitamin D level: 25-Hydroxyvitamin D [25(OH)D] is the active metabolite form that should be measured in the blood to determine vitamin D status – levels of 32 is minimal, optimal is 45-70 ng/mL – EXCERPT, REF
- 25-Hydroxyvitamin D [25(OH)D] is the metabolite that should be measured in the blood to determine vitamin D status
- On a sunny day your body can make thousands of units of vitamin D per 15-30 minute exposure without sunscreen – EXCERPT
- Vitamin D2 (Ergocalciferol) – is kind of a “fake” vitamin D – EXCERPT
- Vitamin D sun lamps are also available [I didn’t know that, if true should our aged care facilities have these?]
2007
July 16, 2007 – NEJM | Review Article: Vitamin D Deficiency by Michael F. Holick, M.D., Ph.D. – READ, via Researchgate – READ, Dr Holick – WEBSITE
2006
September 7, 2006 – Cambridge Uni Press: Epidemic influenza and vitamin D – Cannell et al – READ
2004
September 2004 – Continuing Medical Education: The clinical importance of Vitamin D (Cholecalciferol): A paradigm shift with implications for all healthcare providers by John Cannell et al – READ,
- “With the discovery of vitamin D receptors in tissues other than the gut and bone—especially the brain, breast, prostate, and lymphocytes—and the recent research suggesting that higher vitamin D levels provide protection from diabetes mellitus, osteoporosis, osteoarthritis, hypertension, cardiovascular disease, metabolic syndrome, depression, several autoimmune diseases, and cancers of the breast, prostate, and colon, we can now utilize vitamin D for a wider range of preventive and therapeutic applications to maintain and improve our patients’ health” [italic added]
- “Vitamin D is an endogenous, naturally occurring, photochemically-produced steroidal molecule with essential functions in systemic homeostasis and physiology, including modulation of calcium metabolism, cell proliferation, cardiovascular dynamics, immune/inflammatory balance, neurologic function, and genetic expression.”
- Current daily supplementation recommendations of 200–600 IU are insufficient
- “…many cells and tissues of the body have the ability to metabolize vitamin D, we should not be surprised that vitamin D plays a role in the function of these cells”
March 2004 – American J. Clinical Nutrition: Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis – Holick – READ, [This has been know since 2004 for high risk groups, elderly and the obese, yet no vit D supplementation was recommended for prevention of COVID-19 symptom escalation in 2020 – i.e. to Flatten the Curve]
- “The elderly are at risk for vitamin D deficiency because of poor dietary vitamin D intake and decreased exposure to sunlight.”
- Healthy adults 18-29 y of age can also be vitamin D deficient – depending on their exposure to sun
- Obesity is often associated with vitamin D deficiency…it is efficiently deposited in the large body fat stores and is not bioavailable”
- UVB radiation above 290 nm …is responsible for producing previtamin D3 in the skin.
- “…when the angle of the sunlight (zenith angle) reaching the Earth’s surface is very oblique (ie, early morning, late afternoon, and winter), sunlight must pass through more ozone, which efficiently absorbs the previtamin D3-producing UVB photons, and thus very few, if any, reach the earth’s surface. Because the zenith angle is dependent on time of day, season of the year, and latitude, those factors have a dramatic effect on the cutaneous production of vitamin D3“
2004 – The Vitamin D Council: Vitamin D Toxicity – ARCHIVE
- “Articles about vitamin D are beginning to appear everywhere. For years, most of us wrongly assumed we had enough if we drank a little milk and took a multivitamin pill. Now, headlines around the world are reporting most of us are deficient and those deficiencies are causing numerous illnesses.” – REF
- “Vitamin D is safe when used in the doses nature uses”
- “Most of us make about 20,000 units of vitamin D after about 20 minutes of summer sun. This is about 100 times more vitamin D than the government says you need every day.” – REF
- International Vitamin D Workshops have been conducted since 1973 – ARCHIVE
2002
December 28, 2002 – British J Nutrition: Vitamin D in preventive medicine: are we ignoring the evidence? – Zittermann A. – READ, PDF
- “There is mounting evidence for a pivotal role of vitamin D in the immune system“
- “Macrophages represent the first unspecific defence line of the immune system. Calcitriol increases the activity of lysosomal enzymes in macrophages and facilitate cytotoxic activity by enhancing the rate of phagocytosis.”
- “Data relating infectious diseases to vitamin D status are scanty. However, there is some evidence from epidemiological data for a link between low vitamin D status and an increased risk for infections.”
