Beginning with a May 31, 2013 Science article titled “Accelerating Next-Generation Vaccine Development for Global Disease Prevention” by Plotkins et al, the Robert Wood Johnson Foundation granted $378,000 to the International AIDS Vaccine Initiative (IAVI) on December 16, 2013 to convene international scientists and public-health experts to explore the creation of a Human Vaccines Project that could collectively leverage technological advances to accelerate the development of new vaccines.” [1]

The Human Vaccines Project (HVP) is a global non-profit, public-private partnership (PPP) that brings together leading stakeholders across academia, Big Pharma giants, governments and nonprofits. it was officially conceived in at that confrence on February 5-6, 2014 attended by Stanley Plotkins and 34 other leading vaccine scientists.  They needed to overcome scientific hurdles that impeded the development of revolutionary new vaccines. [2, 3]

Their mission is to “accelerate the development of vaccines and immunotherapiesagainst major global infectious diseases and cancers by decoding the human immune system.” They believe today’s diseases “are much more insidious and biologically complex than those we conquered in the past [4, 5]… and we remain unprepared against the next pandemic.” so “a new approach is needed.” or as they say today “Pioneering a New Era of Human Health”

In July 2014, 20 business leaders from the public and private sectors recommended the Project be structured as a global, nonprofit research and development (R&D) consortium closely engaged with industrial partners, and affiliated with one or more academic centers conducting vaccine R&D…leadership of the Project will then transition from IAVI, its initial catalyst.” [6]

“The Human Vaccines Project has embarked on a decade-long, $1 billion mission to decode the human immune system,” to fight diseses including pandemic flu.  Announced July 1, 2016, applying machine learning should accelerate the plan.  (Alot is ALREADY known).  By October 2, 2022 with the head of IAVI, then HVP, Wayne Koff becomes the CEO & President of the Human Immunome Project, along with Australia’s Nobel Laureate Dr Peter Doherty and MANY more. [7]

  • Feb 13, 2015 – GSK provides grant to establish the Project’s global consortium and plan its research program
  • July 16, 2015 – Vanderbilt Uni Med School joins as first science hub
  • Oct 13, 2015 – AstraZeneca‘s biologics R&D arm MedImmune joins
  • Oct 23, 2015 – Johnson & Johnson (Janssen) joins
  • Jan 14, 2016 – Sanofi Pasteur signs a funding agreement for helping establish the $1B Human Immune Project
  • Feb 10, 2016 – Regeneron joins
  • March 22, 2016 – Pfizer joins to help decode the immune system
  • Jan 4, 2017 – Moderna joins to help help decode the immune system
  • May 8, 2017 – Human Immune Project launched [WEB]
  • Oct. 26, 2017 – HVP launched their Universal Influenza Vaccine Initiative (UIVI) led by Vanderbilt University Medical Center – since “seasonal vaccines are not consistently effective”
  • Jun 28, 2018 – Australia’s Seqirus (CSL Ltd.) partners with project’s UIVI, on 100 year anniversary of 1918 pandemic
  • July 2022 – Universal Coronavirus Vaccine Initiative  for SARS-X, to stop the next pandemic [8, 9]
  • October 2022 – the Human Immunome Project combining systems biology with artificial intelligence, is released

On April 34, 2020 the HVP launched the COVID Vaccine Initiative (CVI) to accelerate COVID-19 vaccine development “for those most vulnerable”. [4]