Coming soon to a supermarket near you – edible vaccines…and it’s been on the cards for a while now.
I first started hearing about vaccines in food sometime in 2022 (maybe earlier) but didn’t have time to investigate, and kind of dismissed it as a bit far-fetched! But I am seeing more and more content on this topic in recent weeks so I stopped to take a look…and as such have started this page to collect those data points to capture the history, and the emerging information about “vaccines” or “foreign proteins” in our food supply, both plant and animal. Included also are emerging mRNA veterinary vaccines, as what goes into our pets, may also go into livestock, which the latter we consume.
How long has this been in the mind of Bill Gates scientists?
A Substack by Attorney Thomas Renz on April 3, 2023: Eat Your Vaccines!… I Mean Vegetables! … Said Bill Gates, has prompted me to launch this page.
Tom noted a September 2000 Scientific American article titles Edible Vaccines which showed the theory of how ingestible immunisation was in the minds of scientists starting in the mid 90’s, which was spurred on by The World Health Organisation asking to for help to solve a “health” crisis of under vaccination.
This is all happening around the time biotechnology and GMO was was beginning to expand and explore it’s possibilities. [Also explore 2000 timeline]
The 2000 article shows How to make an edible vaccine and theoretically how the plant can produce the antigen to allegedly stimulate your body to produced “memory” protection! This theory began in 1995 from when it was “established that plants could indeed manufacture foreign antigens in their proper conformations.”
So a question is, now that there is evidence the “vaccine” genetic message could possibly integrate into the host’s DNA, and that mRNA vaccines are being rolled out in livestock – what is the potential for that animal “vaccine” to produce an antigen protein, that when their flesh is consumed by humans, the person is then indirectly and unknowingly getting “vaccinated”? Or maybe from the salad eaten on the side!
Also review – Vaccine Platforms – HERE
With these products/technologies in development, and already released, what happened to “informed consent”???
Links pertaining to “edible vaccines”, or livestock genetic vaccines – in reverse chronological order
This page is continuously being updated
2023
December 1, 2023 – Malone Substack: Modified mRNA Vaccines for Livestock and Cattle – An update with Drs. Brooke Miller, MD and Robert Malone, MD – WATCH & READ
October 26, 2023 – Sasha latypova Due Diligence Substack: Genetic Vaccines in Animals/Food Supply, Part 1 – Merck Sequivity – RNA particle swine vaccine approved by USDA in 2021 – READ, Part 2 – READ
- Cell transfecting vaccines (3rd generation) include include gene-based (DNA and RNA) vaccines, viral-vector platforms, and live or inactivated chimeric vaccines…many are currently used in animal vaccinations – including farmed fish.
October 3, 2023 – Epoch Times | Crossroads: Your Next Salad Could Vaccinate You – WATCH, EXCERPT
- September 27, 2023 – Vigilant Fox- Rep. Thomas Massie: “Transgenic Edible Vaccines”: Your Next Salad Could Vaccinate You – USDA and FDA research funding for edible vaccines restricted
September 30, 2023 – Gateway Pundit: HORRIFYING: Rep. Thomas Massie Exposes Taxpayer-Funded “Transgenic Edible Vaccines” Which Turns Edible Plants Like Lettuce and Spinach Into mRNA Vaccine Factories to Replace mRNA Shots – READ, TWEET, WATCH
September 14, 2023 – Vigilant Fox: Beef Company CEO: “I’ll Shut Down the Company Before We Ship a Single Bag With mRNA-Injected Meat” – States Jason Nelson, CEO of Prepper All Naturals – READ
August 15, 2023 – Senator Ralph Babet: Asks Minister for Agriculture ( Hon. Murray Watt) about mRNA being injected into Australian livestock intended for human consumption – WATCH
- Currently no mRNA vaccines registered for use in livestock in Australia, and no mandatory vaccines under the Biosecurity Act.
- Meat & Livestock Australia (MLA) have funded a project which is currently being undertaken by NSW govt. – trial underway in Canada to determine whether “safe and effective for animals”…not for consumption
- The Australian Pesticides and Veterinary Medicines Authority (APVMA) has the role of evaluating safety and efficacy of veterinary vaccines and chemicals before registering them for use [good to know]. They are also responsible for food labelling – EXCERPT
- Minister defering to “mRNA is a natural part of bodies”, neglecting that modified mRNA is not natural.
- Re mandatory in the future to inject mRNA products into livestock “No” – EXCERPT
June 16, 2023 – Bannons War Room Episode 2813: Dr. Peter McCullough: “We need a complete ban on Messenger RNA moving into livestock” – WATCH, FULL
June 14, 2023 – Spectator Australia: mRNA vaccines fast-tracked for Australian agriculture – READ
May 4, 2023 – Colleen Huber Substack | The Defeat of COVID: mRNA Vaccines in Food? Don’t Worry – COVID vaccines containing the most stable lipid nanoparticles have resulted in the most vaccine injuries. So how can we scrub those lipids down if they arrive to our food? – READ Are edible vaccines a threat?
May 2, 2023 – Meat and Livestock Australia (MLA): MLA funds mRNA technology project to rapidly produce emergency animal disease vaccines – READ, CREDIT, Hinted to in October 2022 – READ
- Sold as: “Next-generation (mRNA-based) vaccine technologies may provide a game-changing approach to emergency disease preparedness.” as “Live vaccines cannot be imported to Australia.”
- “This project will develop a mRNA vaccine pipeline initially for [lumpy skin disease] LSD, but potentially for other emergency diseases,” said Michael Laurence, MLA’s Program Manager for Animal Wellbeing….”Success of this project might provide a pilot vaccine suitable for use in Australia in less than two years,”” But it is an “over-arching five-year program”
- “The program includes mRNA vaccine development for the two main strains of foot-and-mouth disease as well as exotic Bovine pestivirus and Border disease in sheep…”
- [sold as for “emergency” use then rolled into all jabs, just as it has for COVID-19, now human vaccines for influenza, RSV etc are becoming mRNA based]
April 25, 2023 – CHD with Dawn Richardson: Vaccinated Through the Food Supply: “Transmissible mRNA Vaccines Are a Thing” – with Thomas Renz – WATCH, Genetic Manipulation + Informed Consent With Attorney Tom Renz – READ
“There was a study out of China. They injected a cow with an mRNA vaccine; that cow’s milk then vaccinated the mice that were in the study,”
reported Attorney Tom Renz
April 21, 2023 – McGill: Gene-Therapied Pork or the Fear of RNA Vaccines in Livestock – Some pigs are immunized using RNA vaccines, which anti-vaxxers are claiming are not tested for safety and could harm us. This is not true. – READ “Joe Mercola, snake oil salesman supreme” [Remeber the true snake oil salesman was “Devil Bill” Rockefeller! ]
April 19, 2023 – Modern Farmer: Plant Vaccines Delivered Via Microneedle Could Offer Alternative To Chemical Spraying – READ
- “Scientists have developed the first silk microneedle to deliver drugs to plants.” – PAPER
- “Imagine a world where on-farm robots can deliver tiny injections into each plant, rendering crops resistant to the latest disease or rampant pest….This is how a group of biomaterial scientists and engineers are envisioning the future of crops after developing the first microneedle-based drug delivery technique for plants.”
April 17, 2023 – Tom REnz Substack: mRNA IS in Food – There’s ONLY 1 Way to Stop This – READ
April 17, 2023 – Courageous Discourse Substack: Veterinary Replicon Vaccines – Massive Genetic Effort in Veterinary Medicine Described as “Elegant” – READ
- “Compared with human medicine, veterinary medicine is far ahead in genetic vaccine technologies. One of the reasons is that the life cycle of a livestock is sufficiently short that clinical studies simply aim to demonstrate efficacy with reasonable safety as a secondary goal.”
- “…self-replicating viral RNAs (replicon vaccines) have been developed”
April 16, 2023 – Community Hubb: Vaccines in your salad? Scientists growing medicine-filled plants to replace injections – READ, CREDIT
April 14, 2023 – Courageous Discourse Substack: Edible Vaccines: Promises and Challenges – Vaccine Ideology has Crept into Food Delivery Mechanisms over Recent Years – READ
April 3, 2023 – Tom Renz’s Substack: Eat Your Vaccines!… I Mean Vegetables! … Said Bill Gates – and Missouri HB1169 Bill to stop it – READ
April 2, 2023 – Daily Clout | Dr Naomi Wolf: mRNA Gene Therapy Is Coming to the Food Supply: What We Can Do About it w/ Attorney Tom Renz – WATCH, READ, READ2
April 2, 2023 – Tom Renz on Twitter: BREAKING NEWS: the lobbyists for the cattleman and pork associations in several states have CONFIRMED they WILL be using mRNA vaccines in pigs and cows THIS MONTH. – TWEET
January 24, 2023 – Malone Institute: mRNA Vaccines in Livestock and Companion Animals are here now – READ
January 12, 2023 – Robert Malone Substack: mRNA Vaccines in Livestock and Companion Animals are here now – READ, Why are we not able to view the clinical trials involving animal health?
2022
December 20, 2022 – Preprint: An oral vaccine for SARS-CoV-2 RBD mRNA-bovine milk-derived exosomes induces a neutralizing antibody response in vivo – Zhang et al – READ, ARCHIVE
October 26, 2022 – Meat and Livestock Australia (MLA): Op-ed – Investing in vaccine development and strategies to protect our industry- by Managing Director of MLA! – READ – Foot and Mouth Disease (FMD) gets the “foot” in the door for justifying mRNA vaccines…
- In August 2022 – “University of Melbourne’s Centre of Excellence for Biosecurity Risk Analysis modelled the current risk [of FMD] at an 11% chance of incursion” allegedly “many people are asking the question: why are we not vaccinating livestock now?”
- “Guided by the [Australian Veterinary Emergency Plan] AUSTVETPLAN, the decision on what approach to take in the event of an outbreak is made by the Consultative Committee on Emergency Animal Disease (CCEAD). The CCEAD is a coordinating body providing the technical link between industry, the Australian Government, and state and territory governments for decision making during animal health emergencies”
- “We are also investing in cutting edge science to boost industry’s preparedness, having selected a vaccine for LSD as the first topic for research into mRNA vaccines. We are working with a range of research partners on this initiative.”
- “…a new vaccine would need to go through regulatory approvals” [Good to know! Which begs the question what is the regulatory pathway for an agricultural vaccine?]
- “MLA is providing $1.3 million in funding to an Indonesian FMD vaccine support project” looking ar mRNA vaccines for FMD – REF, Funding announced Aug 2022 – READ
October 17, 2022 – Advanced Materials: Drug Delivery in Plants Using Silk Microneedles – Cao et al – READ, CREDIT
September 28, 2022 – NSW Gov | Minister for Agriculture: NSW fast tracks mRNA FMD [Food and Mouth Disease] and Lumpy Skin Disease vaccines – Tiba Biotech – ARCHIVE A “biosecurity investment” of $65 million.
- “…an important milestone towards securing the vaccine technology that will protect Australia’s $28.7 billion livestock industry” want vaccines ready by August 2023!
- “COVID-19 demonstrated to us that all possible avenues in developing vaccines must be explored and we will leave no stone unturned.”!!
- “This type of vaccine technology may not require the longer testing and approval processes required for conventional vaccine development and importation as it does not use animal products” [Why?]
September 27, 2022 – TIBA BioTech: A Foot and Mouth Disease mRNA Vaccine Deal Has Been Signed Between the NSW Government and US Company Tiba Biotech – READ, ARCHIVE, CREDIT
August 11, 2022 – Meat and Livestock Australia (MLA): A message on biosecurity from the MLA Managing Director – READ, RE: Foot-and-mouth disease (FMD) and lumpy skin disease (LSD) – WEBPAGE
- “Australia is currently free from FMD and LSD and it’s our top priority to keep it that way”
- Sparked by recent cases of FMD and LSD in Indonesia and Bali – Australia can now justify investing in mRNA vaccines! First by funding development in Indonesia [see how it is done?!]
- [Just a reminder re FMD – Imperial Model czar Prof. Neil Ferguson got it wrong in 2001 – TIMELINE]
July 12, 2022 – Animal Health Australia: Vaccines for Lumpy Skin Disease: where are we at? – READ, ARCHIVE [Setting up the “New Era” for mRNA vaccines in Australia]
February 14, 2022 – Viruses: mRNA Vaccine Development for Emerging Animal and Zoonotic Diseases – Le et al – READ, CREDIT
- “Recently, the successful application of mRNA vaccines against COVID-19 has further validated the platform and opened the floodgates to mRNA vaccine’s potential in infectious disease prevention, especially in the veterinary field.
- We also provide an overview of mRNA vaccines developed for animal infectious diseases and discuss directions and challenges for the future applications of this promising vaccine platform in the veterinary field.”
- [What is the consequences when mRNA generated proteins and LNP flood the waterways?, What industry body assures that safety? It certainly is NOT the Gene Technology Regulator – they only look at GMOs]
January 6, 2022 – Australian Veterinary Emergency Plan – AUSVETPLAN – A NEW ERA – READ, ARCHIVE, MLA- CREDIT – guiding mRNA vaccine introduction into Aust.
January 2, 2022 – SciTech Daily: Grow and Eat Your Own Vaccines? Using Plants As mRNA Factories – READ, CREDIT
- “The future of vaccines may look more like eating a salad than getting a shot in the arm. UC Riverside scientists are studying whether they can turn edible plants like lettuce into mRNA vaccine factories”
2021
September 16, 2021 – News Medical Life Sciences; Researchers aim to develop edible plant-based mRNA vaccines – READ
September 16, 2021 – Study Finds: Vaccines in your salad? Scientists growing medicine-filled plants to replace injections – READ
- The University of California-Riverside “team says if they’re successful, the public could eat plant-based mRNA vaccines — which could also survive at room temperature.”
September 16, 2021 – University of California: Grow and eat your own vaccines? – “The future of vaccines may look more like eating a salad than getting a shot in the arm” – READ, ARCHIVE
- “Experimental mRNA vaccines will be edible, Juan Pablo Giraldo, an associate professor in UCR’s Department of Botany and Plant Sciences who is leading the research explained in a press release – (Gateway Pundit) REF
- “Ideally, a single plant would produce enough mRNA to vaccinate a single person,” said Juan Pablo Giraldo, an associate professor in UCR’s Department of Botany and Plant Sciences who is leading the research, done in collaboration with scientists from UC San Diego and Carnegie Mellon University. “
- Project grant $500,000 from the National Science Foundation
“We are testing this approach with spinach and lettuce and have long-term goals of people growing it in their own gardens,” … “Farmers could also eventually grow entire fields of it.”
Giraldo said.
“Our idea is to repurpose naturally occurring nanoparticles, namely plant viruses, for gene delivery to plants,” Steinmetz said. “Some engineering goes into this to make the nanoparticles go to the chloroplasts and also to render them non-infectious toward the plants.”
- Also “The National Science Foundation has granted Giraldo and his colleagues $1.6 million to develop… targeted nitrogen delivery technology” into chloroplasts.
July 8, 2021 – National Geographic: Your next vaccine could be grown in a tobacco plant – Long-awaited plant-based vaccine technology could help COVID-19 shots reach developing countries – READ, ARCHIVE
- [The Justification] “The COVID-19 pandemic has exposed glaring gaps in the world’s current vaccine production capacities. Conventional vaccine manufacturing is costly and complex.”…”Conventional vaccines also have to be kept cold, some as cold as -76 degrees Fahrenheit…”
- “Although there are no plant-based vaccines available for human use, several are in the pipeline.”
- July 2021 – “Medicago, a Canadian biotechnology company, has developed a plant-based COVID-19 vaccine that is currently in phase three clinical trials.” – PIPELINE
- Medicago “Leading the way in plant-based vaccine technology” – REF
- Canada “…plant-derived adjuvanted COVID-19 vaccine candidate rolling submission on April 19, 2021.” – REF
- “Medicago’s plant-derived vaccine candidate against COVID-19 uses Coronavirus-Like-Particle (CoVLP) technology with the vaccine composed of recombinant spike (S) glycoprotein expressed as virus-like-particles (VLPs) co-administered with GSK’s pandemic adjuvant. Two doses of 3.75 micrograms of CoVLP are administered 21 days apart.”
- “On March 12, 2020, Medicago announced the successful production of Virus-Like Particle (VLPs) of the coronavirus just 20 days after obtaining the SARS-CoV-2 (virus causing the COVID-19 disease) gene. Production of VLPs is the first step in developing a vaccine against COVID-19 before preclinical testing for safety and efficacy.” – REF
- “South Korean government has invested $13.5 billion toward plant-based vaccine research” – REF
- December 2021 “Kentucky BioProcessing, the U.S. biotechnology wing of the British American Tobacco Company, announced its plant-based COVID-19 vaccine was entering phase one clinical trials”
- October 2021 “Japanese-owned Icon Genetics GmbH launched phase one clinical trials for its plant-derived norovirus vaccine” [Noroviruses are responsible for approximately 20% of all cases of acute gastroenteritis worldwide. – REF]
- “By one estimate, the plant-based vaccine market value is predicted to rise from $40 to $600 million over the next seven years.”
“The plant-made vaccine industry has been moving slowly but surely forward….What I am really hoping is that [a vaccine to COVID-19] opens the floodgates for new advances in plant-made vaccine development, because now we will see some successes.”
Kathleen Hefferon, professor of microbiology at Cornell University
- “Plant-based vaccines eliminate the need for bioreactors because they themselves are the bioreactors. Plants can be grown in climate-controlled, pharmaceutical-grade greenhouses ….The agrobacteria in this greenhouse are altered to contain a small piece of DNA from the influenza or COVID-19 virus. While the plants are submerged, a small vacuum sucks at the plant’s roots causing the leaves to collapse and shrivel up. A few seconds later, the vacuum is released, causing the leaves to re-expand and, like a sponge, soak up the liquid carrying the agrobacteria, which spread throughout the entire vascular structure of the plant.”…”The agrobacteria transfer the viral DNA to the plant cells, which then make millions of copies of virus-like particles that serve as antigens but are not infectious.” – WATCH
- “lettuce-based vaccines for humans and animals are under development, but none have advanced to clinical trials” – Henry Daniell, researcher at the University of Pennsylvania [NIH & Gates Foundation funding]
- “an emerging new concept, freeze-dried plant cells (lettuce) expressing biopharmaceuticals (fused with transmucosal carriers) are protected in the stomach from acids/enzymes but are released to the circulatory or immune system when plant cell walls are digested by microbes that colonize the gut.”
The justification – WHO statement – [with NO citations] – ARCHIVE
July 6, 2021 – Tim Truth: MAGNET MEAT?! Many Cases Popping Up Of Magnets Sticking To Package Meat. Contaminated Food Supply?! – Compilation of videos – WATCH
- Consider this: mRNA products used for domestic animals destined for the supermarket shelf, and compare it to the magnetism phenomeon in people around the same time – HERE
June 8, 2021 – Merck PRESS RELEASE: Merck Animal Health Expands its SEQUIVITY® Platform to include Sapovirus – New Vaccine Solves for Emerging Enteric Disease in Young Pigs – READ, Swine products – WEB
June 4, 2021 – Global News Wire: Global Plant-based Vaccines Market to Surpass US$ 584.1 Million by 2028, Says Coherent Market Insights (CMI) – READ, CREDIT
April 15, 2021 – Frontiers in Veterinary Science: Novel Vaccine Technologies in Veterinary Medicine: A Herald to Human Medicine Vaccines – Aida et al – “a review of commercially available novel vaccine technologies currently utilized in companion animal, food animal, and wildlife disease control.” – READ
- “The efficacy of inactivated vaccines can be suboptimal with particular pathogens and safety concerns arise with live-attenuated vaccines.” [Really!! now they tell us!]
- “Additionally, the rate of emerging infectious diseases continues to increase and with that the need to quickly deploy new vaccines. [Justification!] Unfortunately, first generation vaccines are not conducive to such urgencies.”
- “These third generation vaccines, including DNA, RNA and recombinant viral-vector vaccines, induce both humoral and cellular immune response, are economically manufactured, safe to use, and can be utilized to differentiate infected from vaccinated animals.”
2020
October 13, 2020 – Lancet: First human efficacy study of a plant-derived influenza vaccine – Tregoning – READ, CREDIT
- “In 2018, Medicago’s flu vaccine was the first in the world to complete phase three clinical trials.” – REF
August 28, 2020 – Canadian Cattlemen Magazine: Vet Advice: mRNA transforms science behind vaccine development – READ
- “SARS-CoV-2, the agent implicated in the ongoing COVID-19 pandemic, pried doors open for a new generation of vaccine development, the newest being messenger RNA (mRNA) technology.”
2019
November 22, 2019 – Molecular Biotechnology: Edible Vaccines: Promises and Challenges – Kurup & Thomas – READ, CREDIT
- “But the main challenge faced by edible vaccine is its acceptance by the population so that it is necessary to make aware the society about its use and benefits.”
- “In January 2005, WHO conducted a meeting regarding the regulatory evaluation of plant-based vaccine. The meeting ended up by concluding that the existing guidelines for development, evaluation, and use of vaccines made by conventional methods can be applied in the production of edible vaccines.”
January 31, 2019 – Clinical and Experimental Vaccine Research | South Korea: A national project to build a business support facility for plant-derived vaccine – Choi & Kim – READ, ARCHIVE, CREDIT
- “For the first time in South Korea, a facility to produce plant-derived vaccines and support bio-venture companies will be built in Pohang, Gyeongbuk Province…” for $13.5 billion
- “Plant-derived vaccine is a recombinant protein (antigen) produced by introducing disease-causing gene to plant organism or plant cells, and it has been reported to be more safe, economical, and fast-paced compared to the existing vaccine production platforms such as egg white and/or mammalian cells”
- 2006, a chicken Newcastle disease vaccine made from carrot cells was first approved by the U.S. Department of Agriculture (USDA) – PAPER
- 2012 a human Gaucher disease treatment from carrot cells was first approved by the U.S. FDA – PAPER
- 2013, Japan developed a dog periodontal treatment using interferon-producing genetically modified strawberries
- 2014, ZMapp, a treatment for Ebola disease was produced in tobacco, greatly increased the world’s interest in plant-derived pharmaceuticals
- “plant-derived vaccines are emerging as a way to prevent and treat rapidly spreading epidemic, including livestock diseases. For example, if you produce a flu vaccine, it takes about six months with egg white, while a plant-derived vaccine can be produced within a month, so you can respond quickly to a rapidly spreading epidemic. And there is no risk of spreading pathogens because plant-derived vaccines are produced through the introduction of recombinant genes, and it is possible to produce about 50 doses of flu vaccine per tobacco plant.”
2018
December 21, 2018 – Plant Biotechnology Journal: Cold chain and virus-free oral polio booster vaccine made in lettuce chloroplasts confers protection against all three poliovirus serotypes – Daniell et al – READ, Bill and Melinda Gates Foundation grant OPP1031406- Also funded other STUDIES
November 13, 2018 – Frontiers in Immunology: A Preliminary Study of a Lettuce-Based Edible Vaccine Expressing the Cysteine Proteinase of Fasciola hepatica for Fasciolosis Control in Livestock – Wesolowska et al – READ
- “Oral vaccination with edible vaccines is one of the most promising approaches in modern vaccinology. Edible vaccines are an alternative to conventional vaccines…Here, freeze-dried transgenic lettuce expressing the cysteine proteinase of the trematode Fasciola hepatica (CPFhW) was used to orally vaccinate cattle and sheep against fasciolosis,…”
July 24, 2018 – Government of Canada: Environmental assessment for Merck Animal Health’s RNA Particle Prescription Products for Swine Influenza and other disease agents – READ
June 8, 2018 – Global Ag Media: 2018 World Pork Expo: Merck Animal Health Launches SEQUIVITY – Joe Roder, DVM, technical services manager, Merck Animal Health – WATCH, ARCHIVE,
- PigSite: Merck Animal Health Introduces SEQUIVITY™ Technology – READ
- “After receiving the sequence, it is synthesised into RNA and inserted into the SEQUIVITY platform, which generates RNA particles. When injected in the animal, these particles provide instructions to the immune cells to translate the sequence into proteins which act as antigens.”
June 6, 2018 – Merck PRESS RELEASE: Merck Animal Health Introduces SEQUIVITY™ Technology – Provides swine producers disease specific vaccines to protect herd health – “This innovative and highly advanced RNA Particle Technology is used to create flexible, safe and precise vaccine solutions to new and evolving disease challenges.” – READ, ARCHIVE, CREDIT
- 2018: Merck WHITE PAPER: Sequivity RNA Particle Technology – Revolutionizing vaccine production – “RNA vaccines, a new class of vaccines, rely on a different way to present an antigen” – an electronic gene sequence is utilized – PDF, ARCHIVE
- BIOLOGICALS OF THE FUTURE –AVAILABLE TODAY
- [Note: Since launching this page in April 2023, Merck has deleted all pages that refer to Sequevity? – SEARCH, or maybe changed domain name?]
- “Millions of doses of the SEQUIVITY vaccine platform have safely been used by veterinarians in swine herds for more than ten years since the USDA first issued the license in 2012.” – PDF, ARCHIVE,
May 10, 2018 – PLOS One: Controlling epidemics with transmissible vaccines – by Nuismer et al – READ [not “edible” but in the ball park of without “informed consent”], Tom Renz – CREDIT
- “Transmissible vaccines are capable of spreading from one individual to another and are currently being developed for a range of infectious diseases.”
2017
October 12, 2017 – Trends in Microbiology: Transmissible Viral Vaccines – Bull, & Nuismer et al – READ, PDF, CREDIT
- “Genetic engineering now enables the design of live viral vaccines that are potentially transmissible…Transmission has the benefit of increasing herd immunity above that achieved by direct vaccination alone but also increases the opportunity for vaccine evolution, which typically undermines vaccine utility.”
February 8, 2017 – Annual Review of Animal Biosciences: Veterinary Replicon Vaccines – Hikke & Pijlam – READ, CREDIT
2016
May 10, 2016 – Genetic Engineering & Biotechnology News: Bayer Partners with BioNTech to Develop mRNA Vaccines, Drugs for Animal Health – READ, Food stuff – READ, CREDIT
April 15, 2016 – Iowa State University: Harrisvaccines Leading the Industry in the Heartland – READ
- The company was founded by Dr. Hank Harris and Dr. Matt Erdman in 2005, and is located in the Iowa State University Research Park – Joint patents with ISU.
- Harrisvaccines is making breakthroughs … a new age approach to the development of vaccines that has turned traditional immunology methods on an ear.”
- “It wasn’t until they connected with a human vaccine producer in North Carolina, Alphavax, that they were able to get the technology licensed.”…”it took more than six years for the technology to gain USDA approval” which “cleared the way for “overnight” success.”
March 15, 2016 – Merck Animal Health Press Release: Harrisvaccines Receives Production Platform Vaccine Licensure First of its Kind Granted by USDA – ARCHIVE, READ, READ, READ, Also see Edible Vaccines – HERE
- Merck Animal Health today announced that its recent acquisition, Harrisvaccines, has been granted licensure of its Prescription Product, RNA Particle (RP) vaccine platform from the U.S. Department of Agriculture (USDA). This first-of-its-kind USDA license approves the company’s innovative production platform and allows for the manufacturing of herd-specific, custom vaccines prescribed by a licensed veterinarian.
- “The vaccine platform and production process used is exactly the same for any disease. The only thing that differs is the gene [RNA sequence] inside the vaccine.” -SerraVax platform REF
2015
November 2015 – ResearchGate: Plant-based vaccines for animals and humans: Recent advances in technology and clinical trials – Takeyama et al – READ
- “The progress toward commercialization of plant-based vaccines takes much effort and time, but several candidate vaccines for use in humans and animals are in clinical trials. “
November 12, 2015 – Merck Press Release: Acquisition Expands and Complements Merck Animal Health’s Strong Vaccine Portfolio – READ, READ, CREDIT, Merck Plans Takeover of Harrisvaccines a 10-year-old company from Ames, Iowa – READ, FiercePharma – READ
- Acquire Harrisvaccines Inc., a privately-held company that develops, manufactures and sells vaccines for food production and companion animals.
- “Harrisvaccines offers innovative technology and an important portfolio of vaccines, with a focus on production animals, an increasingly important segment as consumer demand for protein continues to grow worldwide. The company has a unique RNA Particle technology which represents a breakthrough in vaccine development.”
- The company made headlines in 2013 upon winning government approval of a vaccine against porcine epidemic diarrhea virus (PEDv) and this past fall for the conditional license of a vaccine targeting highly pathogenic avian influenza.” – REF
- Just 4 months (March 15, 2016) later the USDA grants the RP Vaccine Technology PLATFORM full licensure – READ, READ
October 15, 2015 – Vet Practice News: U.S. Orders Stockpile of Avian Flu Vaccine – Harrisvaccines and Ceva Animal Health – READ
September 21, 2015 – USDA Approves Avian Influenza Vaccine – Harrisvaccines – “Avian Influenza Vaccine, RNA uses SirraVax RNA Particle Technology, which permits researchers to adjust the drug to fight future strains.” – READ
May 21, 2015 – National Hog Farmer: Designing a vaccine – READ
- Harrisvaccines is pioneering the commercialization of a novel way to make a vaccine using just a part of a virus. They call it SirraVax RNA Particle, and it’s a technology platform that uses as its backbone a simple virus called an alphavirus” [selling the new technology to the pig farmer]
- “That digital sequence is what goes to Harrisvaccines for development of the vaccine. The specific gene for a virus is placed into the company’s RNA platform where it is then electroporated into Vero cells — a common mammal cell used in labs. The targeted RNA particles are grown in the Vero cells, and then harvested and purified to make the final vaccine.”
- June 10, 2015 – Dr Hank Harris, CEO of Harrisvaccines named Strategic Growth Forum® Entrepreneur Of The Year® 2015 Award Winner – READ
2014
June 17, 2014 – Vet Practice News: Harrisvaccines’ PEDv Vaccine Wins Conditional License – porcine epidemic diarrhea virus (PEDv) – using SirraVax RNA Particle Technology – READ
- “The U.S. Department of Agriculture conditional license — the first granted for a PEDv vaccine — allows Harrisvaccines to sell the vaccine directly to veterinarians and swine producers”…”The company has sold nearly 2 million doses through veterinary prescription since the vaccine was released”
- “The vaccine was introduced in August 2013 under the brand name iPED and quickly gained favor among veterinarians and pork producers. The newly licensed vaccine was renamed Porcine Epidemic Diarrhea Vaccine, RNA, which reflects its SirraVax RNA Particle Technology.”
- The emergency use RNA vaccine was developed in days after Spike gene sequence from China was released!
2013
October 29, 2013 – Press Release: Harrisvaccines, Inc. Secures Exclusive Rights From AlphaVax, Inc. to Develop RNA Particle Vaccines for All Diseases in Companion Animals – READ
- expanded its exclusive license agreement with AlphaVax, Inc. to include all companion animals diseases
- AlphaVax uses a specialized viral vector system to make alphavirus replicon vaccines called alphavaccines – REF
October 22, 2013 – Advances in Biotechnology: Edible Vaccines by Saxena & Rawat (India) – READ
- “In recent years edible vaccine emerged as a new concept developed by biotechnologists. Edible vaccines are subunit vaccines where the selected genes are introduced into the plants and the transgenic plant is then induced to manufacture the encoded protein.
- “Edible vaccines present exciting possibilities for significantly reducing various diseases such as measles, hepatitis B, cholera, diarrhea, etc., mainly in developing countries.” [The developing countries are always the trial “guinea pigs” and used to justify such a technology introduction!]
2012
October 24, 2012 – Harrisvaccines to produce RNA for human vaccines against Ebola, Marburg – Defense Contract – READ, CREDIT
September 20, 2012 – Press Release: Harrisvaccines Announces United States Department of Agriculture (USDA) licensure of the company’s RNA Particle (RP) Platform technology swine flu vaccine, approved by the Department’s Center for Veterinary Biologics (CVB) for disease caused by swine influenza virus (SIV) H3N2 – The vaccine is the first to be licensed by the USDA CVB that utilizes RNA Particle Technology – READ, TIMELINE, REF1, REF2, Harrisvaccines – ARCHIVE
- In 2009 when the license application was submitted to the USDA, they didn’t have an established category into which this new technology product would fit! – REF
- The company also received “United States Veterinary Biologics Establishment License, #592, which approves the Ames-based facility for future manufacture of new vaccines for a broader spectrum of veterinary applications from swine and cattle to companion animal and farmed aquaculture.” – REF
- “We are built to rapidly respond to pandemics as they come into the herd….When the H1N1 virus presented itself we were able to develop a custom vaccine in weeks and were the first to get it to market.”
- Merck: Millions of doses of the SEQUIVITY vaccine platform have safely been used in swine herds for more than ten years since the USDA first issued the license in 2012 – REF, also – PDF, ARCHIVE
- Merck acquired Harrisvaccines in Nov. 2015
- In 2010 Harrisvaccines were sponsored by 21st IPVS Congress – ARCHIVE,
2010
June 24, 2010 – Critical Reviews in Plant Sciences: Plant-Based Vaccines for Protection Against Infectious and Autoimmune Diseases – Carter & Langridge – READ
2007
April 14, 2007 – Transgenic Research: Production of vaccines and therapeutic antibodies for veterinary applications in transgenic plants: an overview – Floss et al – READ, CREDIT
2006
May 2002 – Harrisvaccines Inc. is co-founded by Dr. Hank Harris and Matt Erdman (Postdoctoral Researcher at the time) who is appointed the Chief Technical Officer – READ
February 14, 2006 – PharmExec: The First Plant-Derived Vaccine Approved for Chickens – READ
- “In what is likely the first approval of its kind, the Department of Agriculture gave the thumbs up to a plant-derived vaccine that inoculates chickens against the lethal Newcastle disease. Dow AgroSciences, the vaccine’s manufacturer, said it was the first plant-derived vaccine approved in the world.”
2005
November 2005 – Harrisvaccines Inc. and Iowa State University filed a provisional patent – ARCHIVE
- “While working as researchers at Iowa State University (ISU) in 2005, Harrisvaccines scientists (Drs. Harris and Erdman), discovered that two of the PRRS (Porcine Reproductive and Respiratory Syndrome) surface protein structures allowed the virus to ‘cloak’ itself from the pig’s immune system. These proteins were determined to be the Protective Antigenic Determinants (PAD) for the inducement of antibodies to prevent the PRRS virus in pigs; thus making the proteins the basis for creating a vaccine. Iowa State University filed a provisional patent based on these findings in November of 2005, which has consequently been issued and exclusively licensed to Harrisvaccines.”
- During 2005 Erdman noted that AlphaVax’s replicon platform would be “a good match for delivering the ISU PAD (viral protein elements) as a vaccine”…”Thus, an alliance between the ISU and North Carolina scientists was formed for collaborative research. Subsequently, an evaluation agreement between AlphaVax and Harrisvaccines was signed.”
- “During the evaluation agreement, it was shown by Harrisvaccine scientists that a human vaccine prepared at AlphaVax for influenza would protect pigs against the influenza virus as well. This was the first time that the replicon technology had been used in pigs.
- In 2007, Harrisvaccines and AlphaVax signed an agreement for a field of use exclusive license for the replicon technology to be used in swine for vaccines for PRRS and Swine Influenza (SIV).”
January 24-25, 2005 – WHO Informal consultation on scientific basis for regulatory evaluation of candidate human vaccines from plants – READ, ARCHIVE, PDF
2004
June 23, 2004 – Vaccine: A corn-based delivery system for animal vaccines: an oral transmissible gastroenteritis virus vaccine boosts lactogenic immunity in swine by Lamphear et al – READ, CREDIT, author associated with Oragen Technologies – WEB
- “Recombinant plant expression systems offer a means to produce large quantities of selected antigens for subunit vaccines”!
- “Oral administration of vaccines has the potential to greatly cut the cost and increase the safety of vaccine delivery. In the case of human vaccines, avoiding the use of needles reduces equipment costs, removes the requirement for trained medical personnel to supervise delivery and eliminates safety concerns associated with needle disposal.” [The justification!]
May 12, 2004 – Biosafety Information Centre: Eat up your vaccines – READ, ARCHIVE, Lists edible vaccine trials underway, Naked DNA in ref – HERE
- “There are also considerable risks related to the possibility of a genetically engineered vaccine virus engaging in recombinations with naturally-occurring relatives.” [Like gain-of-function potential, or simply antigen toxicity]
- “These short pieces of DNA are readily taken up by cells of all species, and may become integrated into the cell’s genetic material. … these small DNA fragments can be taken up by cells and multiply and mutate indefinitely. They are known to have significant and harmful biological effects”
- “Upon release or escape to the wrong place at the wrong time, horizontal gene transfer with unpredictable biological and ecological effects is a very serious, and as yet unregulated, hazard.”
- “Antibiotics and traditional vaccines already contribute to horizontal gene transfer. Recombinant vaccines, like those that would be used in edible vaccines, would exacerbate such transfer. This is a serious concern for the release of any genetically manipulated organism, but particularly worrisome in the case of vaccines, because of their disease-causing potential.”…”The ecological and environmental risks of edible vaccines seem to have received little attention, despite the fact that they present major hazards”
- “The risks associated with edible vaccines are particularly worrisome given the medical community’s blind faith in vaccination in general and its seeming unwillingness to take seriously evidence that has been accumulating related to vaccine safety (such as the rise of autoimmune diseases)”
- “Regulators are trying to figure out how to deal with plants engineered to produce drugs….But, as with releases of all genetically modified organisms (GMOs), the parameters considered in determining a product’s ‘safety’ are extremely limited, and do not inspire confidence in dealing with the many and varied risks associated with edible vaccines.”
- “In Melbourne, Australia, CSIRO has grown a measles-fighting tobacco plant and has begun pilot studies with oral plant-based vaccines for malaria and HIV.”
2001
February 2001 [?]: Institute of Science in Society: Horizontal Gene Transfer – The Hidden Hazards of Genetic Engineering – ARCHIVE [relevant to what is happening in the GMO world]
- “Horizontal transfer of transgenic DNA has the potential, among other things, to create new viruses and bacteria that cause diseases and spread drug and antibiotic resistance genes among pathogens. There is an urgent need to establish effective regulatory oversight to prevent the escape and release of these dangerous constructs into the environment, and to consider whether some of the most dangerous experiments should be allowed to continue at all.”
- Open Letter from World Scientists to All Governments Concerning Genetically Modified Organisms (GMOs) – ARCHIVE (started Feb 1999) List of signatories by 2002 – HERE, [sounds similar to what is occurring with Climate scientists]
2000
December 25, 2000 – Grain magazine: EAT UP YOUR VACCINES – second generation of transgenic crops- READ, ARCHIVE
- “Unlike the first generation, which supposedly delivered benefits for the producer, the second generation crops will – we are promised – be designed with the consumer in mind.” functional foods!
September 2020 – Scientific America: Edible Vaccines – PDF
- “antigens delivered in plant foods survive the trip through the stomach well enough to reach and activate the immune system”
September 3, 2000 [?]: Institute of Science in Society (ISIS) Report for the Third World Network: Unregulated Hazards ‘Naked’ and ‘Free’ Nucleic Acids by Traavik et al – ARCHIVE, referenced – HERE
- “A huge variety of naked/free nucleic acids are being produced in the laboratory and released unregulated into the environment. They are used as research tools, in industrial productions and in medical applications such as gene therapy and vaccines.”
- “Nucleic acids are now known to persist in all environments, including the digestive system of animals.”
July 28, 2000 – Genome News Network: Seeds of a New Medicine – Genes, plants, and edible vaccines – ARCHIVE
- “Why edible vaccines? The World Health Organization (WHO) has called for new strategies to deliver vaccines.”
- “Incredible Edible Vaccines” – The banana is targeted because kids love bananas! – PDF
April 2000 – Nature Biotechnology: Edible vaccine success – Savoie – READ, CREDIT
- “ProdiGene (College Station, TX) announced in February that its patented edible vaccine confers protection against the common transmissible gastrointestinal virus in pigs.
- The vaccine, produced from maize genetically modified to express antigens of the virus, is the first of its kind to demonstrate efficacy against a viral pathogen in animal trials and is expected to be commercially available for pigs in two to three years after going through the same US Department of Agriculture approval processes as traditional vaccines.
1999
1999 – Third World Network: Environmental Effects of Genetically Engineered Vaccines? – Traavik – ARCHIVE, referenced – HERE
- “Genetically engineered plants produce “edible vaccines“. Little is known about the consequences of releasing such plants into the environment, but there are examples of transgenic plants that seriously alter their biological environment. A number of unpredicted and unwanted incidents have already taken place with genetically engineered plants.”
- For more bullet points visit my substack – HERE
March 15, 1999 – Virology: Induction of a Protective Antibody Response to Foot and Mouth Disease Virus in Mice Following Oral or Parenteral Immunization with Alfalfa Transgenic Plants Expressing the Viral Structural Protein VP1 – Wigdorovitz et al – READ, CREDIT
1999 – Boyce Thompson Institute (BTI) at Cornell University – Clinical trial of an edible vaccine – Potatoes containing the Norwalk virus (which causes vomiting and diarrhoea) fed to volunteers elicited an immune response in 19 out of 20 subjects. BTI researchers are attempting to engineer vaccines into bananas and have produced powdered tomatoes that carry Norwalk virus DNA.” Grant from Rockefeller Foundation grant – $58,000 for three years – to collaborate with Mexican researchers at the Mexican health agency, CINESTAV. – REF
1998
October 1, 1998 – Nature Biotechnology: A plant-based cholera toxin B subunit–insulin fusion protein protects against the development of autoimmune diabetes – Arakawa et al – READ, CREDIT
May 1, 1998 – Nature Medicine: Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potato – Tacket, Arntzen et al – READ, CREDIT
1997
1997 – “The first human clinical trial of an edible vaccine took place in 1997, when volunteers ate raw potatoes genetically engineered against diarrhoea-causing E coli. Ten of the 11 volunteers who received the vaccine had fourfold rises in serum antibodies.” – REF
1995
May 5, 1995 – Science: Oral Immunization with a Recombinant Bacterial Antigen Produced in Transgenic Plants – Arntzen et al – READ, CREDIT
- By 1995 researchers …had established that plants could indeed manufacture foreign antigens in their proper conformations – REF
