In a Nature article published January 5, 2022, it points to mounting evidence from animal studies that Omicron is poor at infecting deep lung tissue, making it “less dangerous”, the exact prediction made by Dr Malone on December 15, 2021.
Based on modeling, the Omicron variant may have an 88% likelihood of escaping current vaccines, and studies are revealing breakthrough cases with Omicron. In lay terms, the spike protein mutations are too great for the vaccine-induced Wuhan spike antibodies to neutralise. The same appears true for previous natural infection, though second infection is mild.