COVID-19 | Totality of Evidence https://totalityofevidence.com COVID-19 pandemic timeline and research resource links Sun, 05 Jan 2025 08:14:45 +0000 en-AU hourly 1 https://wordpress.org/?v=6.7.1 https://totalityofevidence.com/wp-content/uploads/2022/01/TE-favicon-150x150.png COVID-19 | Totality of Evidence https://totalityofevidence.com 32 32 Remdesivir https://totalityofevidence.com/remdesivir/ Sun, 17 Apr 2022 02:49:27 +0000 https://totalityofevidence.com/?p=3908 Remdesivir is “a nucleotide analogue prodrug that inhibits viral RNA polymerases,” (an intravenous anti-viral drug) made by Gilead Sciences that was pulled from an Ebola trial due to it increasing mortality. [2] Dr Bryan Ardis in early 2020 looked into…

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Remdesivir is “a nucleotide analogue prodrug that inhibits viral RNA polymerases,” (an intravenous anti-viral drug) made by Gilead Sciences that was pulled from an Ebola trial due to it increasing mortality. [2]

Dr Bryan Ardis in early 2020 looked into remdesivir, on the back of losing his father-in-law to this very drug in February 2020, and revealed to the world that the NIH’s promotion of remdesivir as the only allowed hospital treatment for COVID-19 was in fact increasing mortality – a death that was certified as a COVID-19 death! Dr Ardis provides his overview of remdesivir findings at the Grand Jury inquiry – HERE.

Australia’s TGA granted provisional registration for remdesivir (Veklury) in early 2020. [1]

Giliead Sciences – the company that makes remdesivir:

Hospital Protocols force remdesivir onto patients – what hospitals are doing and how to protect yourself and your loved ones

  • Death by Hospital PROTOCOL! – HERE, CREDIT
  • Remdesivir stories at protocolkills.comHERE

Following are links to aid with your own research into Remdesivir

2024

October 4, 2024 – Gateway Pundit: EXCLUSIVE: Military Whistleblower Shares his Motivation for Releasing the Explosive “The Remdesivir Papers” Report – READ under the pseudonym Daniel LeMay

October 4, 2024 – Gateway Pundit: The Remdesivir Papers: Did Service Members Deserve to Die? – READ, Remdesivir Paper – PDF

  • “Data derived from the Department of Defense Joint Trauma System (JTS) by a military whistleblower offers a stark contrast to the results of multiple clinical trials involving the liberal usage of remdesivir in military treatment facilities and other civilian facilities, as well as its potential contribution to, at minimum, hundreds of untimely deaths.”
  • service members and veterans participated in at least four Phase 3 Adaptive COVID19 Treatment Trials (ACTT) between February 2020 and June 2021, to include NCT04280705 [ACTT-1], NCT04401579 [ACTT-2], NCT04492475 [ACTT-3], and NCT04640168 [ACTT-4]. Each of these trials was sponsored by the National Institute of Allergy and Infectious Diseases (NIAID).”…Another trial (NCT04302766) was sponsored by U.S. Army Medical Research and Development Command (USAMRDC). – REF
  • “A true placebo, like saline, wasn’t used other than in circumstances where there were limitations on matching placebo supplies.” – both the treatment and “placebo” received remdesivir! – REF,
  • “Why has the USAMRDC not published data on the number of deaths from participants in NCT04302766 nor the number of deaths of those who may not have been part of the trial itself but were treated with remdesivir in dozens of MTFs around the country?”
  • September 24, 2024 – Gateway Pundit FOIA request – PDF
  • “Four years later, it has been clearly determined that the use of remdesivir can result in many potential organ-based adverse effects.”
  • “were deaths during remdesivir treatment trials wrongly attributed to COVID-19 when they could/should have been attributed to the use of the controversial drug?”

September 23, 2024 – Newsweek: COVID Treatment Recall Issued After Glass Found in Drug – READ

  • The affected lot, identified as 47035CFA, was distributed nationwide in the United States beginning July 16, 2024.
  • September 26, 2024 – CHD: Glass Particles Prompt Another Recall of Remdesivir, the Controversial Drug Hospitals Used to Treat COVID Patients – READ, CREDIT

September 20, 2024 – FDA: Gilead Issues Voluntary Nationwide Recall of One Lot of Veklury (Remdesivir) for Injection 100 mg/vial Due to the Presence of a Glass ParticleREAD, CREDIT

June 2, 2024 – Arkmedic Substack: GileadGate Exposed – Rebekah Barnett’s bombshell FOIA investigation uncovers a web of vested interests in the cover-up of an identified cancer risk related to specific COVID vaccines. – READ

March 9, 2024 – Geoff Pain Substack: Remdesivir Deaths – was Endotoxin a factor? – READ

  • Chemical structure of Remdesivir has organophosphate and cyanide groups but looking at symptoms, could Endotoxin contamination, as found in India, be the caused deaths?

February 2, 2024 – CHD Bus Stories: “They’re Still Killing With Remdesivir” – Nancy Wilson was “forced” to get the COVID-19 shot under mandates, she then tested positive while in hospital, multiple staff asked her to take remdesivir. She declined and took ivermectin instead. Find out how the doctors reacted – WATCH

Jan-Feb 2024 – CHD Bus Stories: Loved one’s killed by COVID-19 hospital protocols, usually involving remdesivir (a small collection of stories):

  • My Wife Was Killed By Hospital Covid Protocol – Clyde “Rick” StephensonWATCH
  • They Killed My Wife In The Hospital She Worked At – Mark Hartshorn’s wife, Jill – WATCH
  • My Wife Survived Covid Hospital Protocol – Richard‘s story – WATCH
  • My Daughter Snuck Ivermectin Into The Hospital – Micheal Murphy‘s story – WATCH
  • Dennis tells the story of his friend, Daniel Freeman, who passed away in the hospital while being treated for the virus – WATCH
  • My Husband Was Killed By Hospital Covid Protocol – Juliana‘s story – WATCH
  • My Mother Died In Hospital During Covid – Kelly warning – WATCH
  • My Husband Was Killed by Covid Hospital Protocol – Cynthia‘s recounts the heart-wrenching details – WATCH
  • They Tried To Kill Me – WATCH
  • My Momma Was Killed By Hospital Covid Protocol – Kristina CroftWATCH
  • They Killed My Healthy Husband – Jill Smith obtained over 6,000 pages of records, 60 of which listed drugs he was administered – WATCH
  • My Husband Survived Hospital Covid Protocol – Robyn‘s story – WATCH
  • Michelle Mixa cousin cousin die in the hospital – WATCH
  • My 30 Year Old Daughter Chasity Anderson Was Killed By A Hospital Chasit – She was put on remdesivir, labeled ‘DNR,’ isolated from family and put on a ventilator, she did not make it out of the hospital alive – WATCH
  • They Killed My Mom With Remdesivir – Crystal shares how her mum went to hospital with abroken hip, they tested for COVID-19 it was positive, she then fell victim to “hospital protocol” for positive test!!! – he mum had “no symptoms, whatsoever,”- WATCH
  • I Survived The Hospital Covid Protocol – Valerie‘s story, more than just a lack of informed consent. While a patient, she made known her wishes about treatment and end-of-life care by writing them on her arm, yet Valerie still felt an “overwhelming fear” about her situation – WATCH
  • Hospital Covid Protocol Death – In August 2021, when his parents tested positive for COVID. While his vaccinated mother was sent home, his father, who had received no COVID shots, was admitted to the hospital to receive “separate treatment.” – Wayne and Mary‘s story – WATCH
  • My Dad Was Killed By Remdesivir – story of Renee’s father – WATCH
  • My Husband Ray Was Killed By Covid Hospital Protocol – WATCH
  • My Husband Survived Hospital Protocol – as an employee of the pharmaceutical industry she was shocked and surprised – WATCH
  • My Dad Was Killed By Hospital Protocol –Andy‘s story – WATCH
  • Hospital Hostage Rescue – Within hours of being admitted, Gail Seiler remembers being told by a doctor that she was going to die but that “the only hope” she had for survival “was remdesivir and a vent.” – WATCH
  • They Killed My Mom – Elizabeth Kucker‘s story – WATCH
  • My Mom Was Killed By Covid Hospital Protocol after 53 days – Genny Rodriguez‘s story, find out what she uncovered from the medical records after the fact. – WATCH
  • My Husband Was Killed By Hospital Protocol – Liz recounts Kevin’s tragic death – WATCH
  • They Killed My Husband – Vanessa Tilley speaks out – WATCH
  • Covid Hospital Protocol Killed My Husband – Lisa Butler shares her husband’s medical records – WATCH

2023

October 18, 2023 – Daily Clout c/ Dr Naomi Wolf: Grace’s Dad (Scott Schara) Tells Heartbreaking Story of His Daughter’s Murder at Hospital – WATCH

  • He and his family lost their lovely, ebullient, formerly perfectly healthy 19-year-old daughter Grace at Ascension Hospital after she was admitted with COVID and an unlawful “Do Not Resuscitate” notification was placed, against her family’s will, in her records.

August 9, 2023 – The Dossier Substack by Jordan Schachtel: Fauci successor at NIAID peddled dangerous Remdesivir drug as ‘silver bullet’ against Covid-19-Dr. Jeanne Marrazzo tried to use unsafe antiviral IV drug on every covid hospitalized patient at UAB. – READ

August 9, 2023 – Rounding the Earth Substack: BOMBSHELL: New FOIA Documents Reveal the COVID Pandemic Was a DoD Operation Dating Back to Obama – Jeanne Marrazzo has been queened to replace Fauci as head of NIAID – insights – READ

  • July 2020, Marrazzo at University of Alabama called using HCQ as “irresponsible and despicable” – she is funded by Gilead pharma for remdesivir trials!

July 28, 2023 – American Thinker: ‘It’s Murder’: Remdesivir Victims Decry FDA’s Shocking New Move by Stella Paul – READ, CREDIT

  • “Remdesivir may be the most despised drug in American history, earning the nickname ‘Run Death Is Near’ for its lethal record during COVID.””

July 24, 2020 – Testimonial – Remdesivir’s typical trail of destruction, knocked out kidneys in 9 days – TWEET , So sorry for your loss Dawn.

July 10, 2023 – Ethical Skeptic: Those who have made arguments that Remdesivir was deadly, have a data to back their contention as a hypothesis. – THREAD

  • Non-Alcohol related Liver Mortality did not arrive with Covid, it arrived with Remdesivir. Now this ICD set has recovered fully to PFE-baseline

May 30, 2023 – Brownstone Institute: Why Are Hospitals Still Using Remdesivir? – Two smoking guns – READ

  • “Alas, the federal government insisted that if hospitals wanted to get paid, they had to treat Covid patients with Remdesivir. The fact that this drug was made by their good friends at Gilead Science and everybody was getting rich from the deals they cut had absolutely nothing to do with it, of course. It was all done for love of the people. But just to make sure that Remdesivir could attain its current billion-dollar status, the feds incentivized hospitals with a 20 percent boost to the entire hospital bill of patients treated with Remdesivir. “
  • CMS.gov – still paying on Veklury (remdesivir) til September 30, 2023, even though emergency officially ended – ARCHIVE, [January 21, 2022 – FDA granted supplemetal approval remdesivir for COVID-19, April 25, 2022 EUA revoked
  • “The 20 largest hospitals enjoyed a 62 percent increase in their combined net assets during those glorious Covid years, providing many top executives with a $10 million salary or more.” Open Books – READ

May 26, 2023 – CHD Th Peoples Testament: COVID Vaccine Injured Police Officer Killed by Remdesivir – guest Karlyn Swoap – WATCH

May 7, 2023 – C’s Newsletter Substack by Charles Wright: The Duality of Steve Kirsch – Remdesivir and Vaccine Adverse Events. – READ

  • Steve Kirsch established Covid Early Treatment Fund (CETF) in April 2020,
  • He let Rockefeller Philanthropy Advisors manage the fund
  • Kirsch’s CETF funded research on several chemical compounds, including Remdesivir.
  • Mr. Kirsch also reported on Twitter that he had a friend at Gilead, the patent holder of Remdesivir.
  • [Reserve your judgement of Steve Kirsch based on his funding of this product at this point in time (April 2020) I’d suggest he was just trying to find an answer, he explains his early journey on June 2021 podcast with Bret Wienstien and Dr Robert Malone. I place this information here to capture the big picture. Everyone is on a journey of “discovery”!]

March 15, 2023 – The Expose: Remdesivir estimated to have killed 100,000 Americans – READ

2022

October 27, 2022 – The Highwire Ep 291 – REMDESIVIR NIGHTMARE: “I ABSOLUTELY BLAME THE HOSPITAL FOR HIS DEATH” – interview with two widows whose husbands lost their lives while on the same COVID-19 treatment protocol at Beaumont Hospital in Michigan – WATCH, FULL

October 18, 2022 – Nature Communications: Effect of remdesivir post hospitalization for COVID-19 infection from the randomized SOLIDARITY Finland trial – Nevalainen et al – READ

September 26, 2022 – Vigilant Fox: Incentivized to KILL: Prescribe Remdesivir, and We’ll Give You a 20% Bonus – EXCERPT, WATCH, Interview with Steve Kirsch – SOURCE, More Dr Marik – HERE

“The hospital bill, the average, is about $400,000 to $500,000 per COVID patient — PER COVID patient.”
[So that’s an $80,000 to $100,000 BONUS]

Dr Paul Marik

September 22, 2022 – The Highwire Ep 286 – LAWYERS SUE HOSPITALS FOR REMDESIVIR DEATHS [ALARMING] – WATCH, FULL

  • The Fauci promoted NIH Remdesivir RCT clinical trail started Feb 21, 2020 enrolling 1100 individuals, it concluded that patients had a “31% better chance of recovering and getting out of the hospital”
  • They changed the trial endpoints from reduced mortality, to days in hospital. They unblinded patient and discharged treatment group from hospital early!
  • Anyone who came to a hospital and “diagnosed” with COVID-19 were put on remdesivir. Hospitals incentivised, patients restrained to beds with cable ties, drugged with morphine, starved, dehydrated, phone remove and isolated from their family – the average time to death on remdesivir is 9 days! = torture
  • Patients threatened if they leave hospital against medical advice, insurance won’t cover hospital cost = blackmail
  • Lawyers have thousands of alarmingly similar testimonies across 32 states.
  • Some clients received 30-40 different drugs, many contraindicated with remdesivir!

September 7, 2022 – Towards The Light: Remdesivir deaths press conference – Fresno, California – WATCH

August 16, 2022 – Gilead PRESS RELEASE: Veklury® (Remdesivir) Demonstrates Continued In Vitro Antiviral Activity Against Omicron Subvariants, Including BA.4 and BA.5 – READ, ARCHIVE

July 30, 2022 – Arkmedic Substack: Welcome to Gilead A scientific scandal with huge implications for women’s health is brewing and you weren’t going to hear about it – until now – Women’s cancer to accelerate – READ

  • Another paper “Spike Impairs DNA Damage Repair” RETRACTED! [peer review or peer pressure!]
  • “…if my suspicions are correct the paper that I’m going to discuss shows that women in every developed country are at risk of a tsunami of women’s cancers.”

July 15, 2022 – Vaccine Safety Research Foundation Episode #38: The Tragedy of Remdesivir – WATCH

April 22, 2022 – WHO now recomends remdesivir – READ, CREDIT

  • “On 22 April 2022, following publication of new data from a clinical trial looking at the outcome of admission to hospital, WHO now suggests the use of remdesivir in mild or moderate COVID-19 patients who are at high risk of hospitalization.”

April 21, 2022 – Gilead Statement on WHO Recommendation of Veklury® (Remdesivir) and Acceleration of Prequalification Submission – READ, ARCHIVE

  • “World Health Organization’s (WHO) Therapeutics and COVID-19: living guideline, which now conditionally recommends Veklury® (remdesivir) for use in the treatment of patients with non-severe COVID-19 at the highest risk of hospitalization.” – WHO document – ARCHIVE
  • “The revised recommendation is based on evidence from our Phase 3 double-blind, placebo-controlled trial (PINETREE) demonstrating that a three-day course of Veklury treatment significantly reduced the risk of hospitalization for non-hospitalized patients at high risk of disease progression.” [They’re testing remdesivir as EARLY treatment – finally!!! – so like Hydroxychloroquine but remdesivir is highly TOXIC]
WHO – source
“any severity” !!!! – WHO – source

February 23, 2022 – Stew Peters: REMDESIVIR HAS BEEN AUTHORIZED FOR USE IN INFANTS – w/ Ali Shultz – infants separated from parents and force remdesivir – WATCH, CREDIT

February 5, 2022 – TGAustralia: TGA approves provisional determination for Gilead Sciences Pty Ltd for COVID-19 treatment, VEKLURY (remdesivir), for proposed use in children and adults who are at risk of progressing to severe COVID-19 – ARCHIVE

February 2, 2022 – The Water Cooler w/ David Brody: Dr. Paul Marik Calls Remdesivir Policy an “Absolute Disgrace” – WATCH, CREDIT

January 21, 2022 – The David Knight Show: HHS Targets Kids, Ends Adult Data Collection – on EUA of Remdesivir for children – WATCH, CREDIT,

  • David Knight summarizes the history of Veklury® (remdesivir) and raises the issue of data manipulation regarding the health of children

January 21, 2022 – FDA PRESS RELEASE: FDA Takes Actions to Expand Use of Treatment for Outpatients with Mild-to-Moderate COVID-19 and to pediatric population down to 3.5kg weight! – READ Three days later monoclonal antibodies were removed as an early treatment option!

January 21, 2022 – Gilead PRESS RELEASE: FDA Approves Veklury® (Remdesivir) for the Treatment of Non-Hospitalized Patients at High Risk for COVID-19 Disease Progression – READ

  • “Approval Based on Phase 3 Data Showing Veklury Significantly Reduced Risk of Hospitalization By 87% Compared with Placebo”
  • NIH Guidelines Recommend Veklury for the Treatment of Non-Hospitalized Patients at High Risk
  • FDA Expands Pediatric Emergency Use Authorization (EUA) to Include Treatment of Non-Hospitalized Pediatric Patients at High Risk

January 27, 2022- NEJM – Early Remdesivir to Prevent Progression to Severe COVID-19 in Outpatients (3-day course remdesivir) – READ

2021

November 17, 2021 – Association of American Physicians and Surgeons (AAPS): Biden’s Bounty on Your Life: Hospitals’ Incentive Payments for COVID-19 – READ

  • The ‘Coronavirus Aid, Relief, and Economic Security Act’’ or the ‘‘CARES Act’’ March 27, 2020 allowed for these incentives
  • “A 20 percent “boost” bonus payment from Medicare on the entire hospital bill for use of remdesivir instead of medicines such as Ivermectin.”

October 18, 2021 – The Blaze: Horowitz: The $cience of remdesivir vs. ivermectin: A tale of two drugs – READ, ARCHIVE

  • A tale of two drugs. One has become the standard of care at an astronomical cost despite studies showing negative efficacy, despite causing severe renal failure and liver damage, and despite zero use outpatient. The other has been safely administered to billions for river blindness and now hundreds of millions for COVID throughout the world and has turned around people at death’s doorstep for pennies on the dollar.”

October 13, 2021 – Cardiovascular Toxicity: Potential cardiotoxic effects of remdesivir on cardiovascular system: a literature review. (Remdesivir is substantially more cardio-toxic than chloroquine) – READ, WATCH

~August 27, 2021 – Awaken America tour: Dr Brian Ardis warns about remdesivir – WATCH, CREDIT

July 15, 2021 – JAMA Network Open: Association of Remdesivir Treatment With Survival and Length of Hospital Stay Among US Veterans Hospitalized With COVID-19 – Ohl et al – READ, CREDIT [toxicity of remdesivir is revealed]

  • “In this cohort study of US veterans hospitalized with COVID-19 at Veterans Affairs facilities, remdesivir treatment was associated with prolonged hospitalization but was not associated with improved survival.”

July 8, 2021 – In the US “COVID-19 Treatment Guidelines”, the NIH knows remdesivir is associated with renal toxicity – See Table 2e pg. 153 – HERE, ARCHIVE, WATCH The table is now referred to as Table 2f – HERE

April 22, 2021 – E Clinical Medicine: Efficacy of the TMPRSS2 inhibitor camostat mesilate in patients hospitalized with Covid-19-a double-blind randomized controlled trial – Gunst et al – PDF , FUNDING, ARCHIVE, Danish study – READ,

  • In this comostat mesiliate trial “some patients received remdesivir and/or dexamethasone as standard of care”!! – CREDIT
    • ““Remdesivir was administered to 96 participants; 64 (47%) in the camostat group and 32 (47%) in the placebo group.”” The study had a total of 208 participants in total of which 46% received remdesivir!
  • The study found “that 200 mg t.i.d. camostat mesilate is not an effective treatment for hospitalized patients with Covid-19”

April 17, 2021 – India – COVID-19: Remdesivir price slashed by nearly Rs 2000 post govt intervention – READ

April 2021 – Remdesivir and acute renal failure: a potential safety signal from disproportionality analysis of the WHO safety database. (Remdesivir was found to have a 20-fold higher renal failure rate compared to three comparable drugs: hydroxychloroquine, tocilizumab, and lopinavir/ritonavir) – READ, WATCH

May 10, 2021 – National Center for Global Health and Medicine (NCGM) JAPAN: Flowchart for the Treatment of COVID-19 in NCGM (adults) 3rd Edition – PDF, ARCHIVE, (NCGM date back to 1868! – PDF)

Remdesivir and low dose corticosteriod the basis of SARS-CoV-2 infection for NCGM hospitals – PDF

March 18, 2021 – American Society of Microbiology: Remdesivir for COVID-19: Why Not Dose Higher?READ, Funded by Steve Kirsh foundation – CREDIT

January 31, 2021 – Forbes: The Strange Story Of Remdesivir, A Covid Drug That Doesn’t WorkREAD, ARCHIVE, CREDIT

January 4, 2021 – WCPO: A new study from the University of Cincinnati is raising concerns about the safety of the FDA approved COVID-19 treatment Remdesivir – WATCH, CREDIT

January 2, 2021 – Springer: Remdesivir in Coronavirus Disease 2019 (COVID-19) treatment: a review of evidence by Jaime Lin et al – READ

  • “Remdesivir, an investigational broad-spectrum antiviral agent has previously demonstrated in vitro activity against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), and in vivo efficacy against other related coronaviruses in animal models.”

2020

November 20, 2020 – NBC News: Remdesivir shouldn’t be used on hospitalized COVID-19 patients, WHO advises (as there is no evidence it improves survival or reduces the need for ventilation). “Remdesivir has potential side-effects on the kidneys, according to data Gilead shared with the European Medicines Agency” – READ, ARCHIVE, READ2

November 20, 2020 – WHO: WHO recommends against the use of remdesivir in COVID-19 patients – ARCHIVE, CREDIT

  • “WHO has issued a conditional recommendation against the use of remdesivir in hospitalized patients, regardless of disease severity, as there is currently no evidence that remdesivir improves survival and other outcomes in these patients.”
  • “On 22 April 2022, following publication of new data from a clinical trial looking at the outcome of admission to hospital, WHO now suggests the use of remdesivir in mild or moderate COVID-19 patients who are at high risk of hospitalization” – REF

November 19, 2020 – BMJ: WHO Guideline Development Group advises against use of remdesivir for covid-19 – READ

November 5, 2020 – NEJM: Remdesivir for the Treatment of Covid-19 — Final Report by Beigel et al [NIH paper] – READ, CNN – this study was used to gain FDA approval – READ

Dr Alexander discussion re paper – SUBSTACK

  • Study design tampering “they made a non patient important outcome (time to recovery), the primary outcome.”
  • “the NIH highly touted and flaunted study that did not report or focus on patient-important objective outcomes and only on reduced time to recovery, was deeply flawed methodologically.” – REF

November 4, 2020 – Under it’s New COVID-19 Treatments Add-On Payment (NCTAP) US CMS.gov provides a 20% bonus payment on the entire hospital bill, just if they administer remdesivir. – LINK, LINK2, WATCH Compared to other treatments remdesivir is below inferior (look at cost of the drugs vs those approved!)!

October 29, 2020 – Pulitzer Center: The ‘Very, Very Bad Look’ of Remdesivir, the First FDA-Approved COVID-19 Drug – READ

  • On October 15, 2020 “The World Health Organization’s (WHO’s) Solidarity trial showed that remdesivir does not reduce mortality or the time COVID-19 patients take to recover.”
  • Science has learned that both FDA’s decision and the EU deal came about under unusual circumstances that gave the company important advantages.” The FDA did not consult their Antimicrobial Drugs Advisory Committee (ADAC).
  • The European Union settle on the remdesivir pricing exactly 1 week before the disappointing Solidarity trial results came out – a $1 billion deal!

October 28, 2020 – Science Innsider: The ‘very, very bad look’ of remdesivir, the first FDA-approved COVID-19 drug – The Food and Drug Administration held no advisory meeting on antiviral, and the European Union signed contract without knowing of failed trial – READ

  • Gilead Sciences, On 8 October, 2020 Gilead Sciences signed an agreement to supply the European Union with its drug remdesivir as a treatment for COVID-19—a deal potentially worth more than $1 billion. Two weeks later, on 22 October, the U.S. FDA approved remdesivir for hopitalised COVID-19 patients in the United States—the first drug to receive that status.

October 25, 2020 – Vox: The FDA approved remdesivir to treat Covid-19. Scientists are questioning the evidence – READ, CREDIT

October 23, 2020 – NBC News: FDA approves first drug for COVID-19: remdesivir. No other Covid-19 drugs have received FDA approval. – READ

October 22, 2020 – The Highwire Ep 186: FAUCI’S REMDESIVIR ‘FALLS FLAT’ – WATCH, BITCHUTE, FULL

  • “In April, Dr. Fauci said the repurposed antiviral, Remdesivir, showed a “clear-cut, significant, positive effect in diminishing the time to recovery.” However, the WHO has now released the findings of its ‘Solidarity Trial,’ encompassing 400 hospitals around the world. Results indicate the drug has ‘fallen flat,’ prompting the WHO to declare it has “little to no effect” on hospitalized COVID-19 patients.”
  • “This is just a drug looking for a purpose” says Del

October 22, 2020 – CNN: Remdesivir becomes first Covid-19 treatment to receive FDA approval – READ

October 22, 2020 – FDA: FDA Approves First Treatment for COVID-19 READ, Label for Veklury – PDF

  • Approved “antiviral drug Veklury (remdesivir) for use in adult and pediatric patients 12 years of age and older and weighing at least 40 kilograms (about 88 pounds) for the treatment of COVID-19 requiring hospitalization.

October 22, 2020 – FDA’s approval of Veklury (remdesivir) for the treatment of COVID-19—the science of safety and effectiveness – READ, REF, Gilead letter – PDF, Product label – PDF

  • Approved for adult patients and children (12 years of age and older and weighing at least 40 kg) requiring hospitalization – “the first drug approved to treat COVID-19
  • “This approval does not include the entire population that had been authorized to use Veklury under a mechanism called emergency use authorization (EUA), which is not the same as approval.
  • “FDA also revised the EUA for Veklury, originally issued on May 1, 2020, to permit the drug’s use for treatment of suspected or laboratory confirmed COVID-19 in hospitalized pediatric patients weighing 3.5 kg to less than 40 kg or hospitalized pediatric patients less than 12 years of age weighing at least 3.5 kg.”
  • “Gilead submitted a study published in the New England Journal of Medicine that showed the drug shortened the course of illness from an average of 15 days to about 11 days in hospitalized patients.” – REF, Study not peer reviewd until Nov 2020 – STUDY – Time to recovery a poor primary endpoint – SUBSTACK

October 20, 2020 – Reuters: EU makes 1 billion-euro bet on Gilead’s COVID drug before trial results – The European Union agreed to pay > 1 billion euros (USD$1.2 billion) to Gilead for a six-month supply of its antiviral drug remdesivir, before the publication of final results of the biggest trial of the COVID-19 medication “The agency [WHO] is investigating remdesivir’s potential adverse effects on kidneys”. – READ

October 16, 2020 – Science: Remdesivir and interferon fall flat in WHO’s megastudy of COVID-19 treatments – READ, ALT

October 15, 2020 – PRESS RELEASE: Gilead Sciences Statement on the Solidarity Trial – READ, ARCHIVE

  • “We are concerned that the data from this open-label global trial have not undergone the rigorous review required to allow for constructive scientific discussion, particularly given the limitations of the trial design.”

October 15, 2020 – NEJM: Repurposed antiviral drugs for COVID-19 –interim WHO SOLIDARITY trial resultsREAD, preprint date – READ2, WHO SOLIDARITY TRIAL COVID-19 core protocol – PDF

  • WHO funded SOLIDARITY trial included: “405 hospitals in 30 countries, 11,330 adults underwent randomization; 2750 were assigned to receive remdesivir, 954 to hydroxychloroquine, 1411 to lopinavir (without interferon), 2063 to interferon (including 651 to interferon plus lopinavir), and 4088 to no trial drug.”
  • ALL had “little or no effect on hospitalized patients with Covid-19, as indicated by overall mortality, initiation of ventilation, and duration of hospital stay.”
  • The regimen for remdesivir (intravenous) was 200 mg on day 0 and 100 mg on days 1 through 9.
  • [note: hydroxychloroquine was not being used in patients this late by the frontline doctors – MORE]

October 15, 2020 – HHS | Public Health Emergency: Veklury (remdesivir): ASPR’s Portfolio of COVID-19 Medical Countermeasures under Investigation – ARCHIVE, SOURCE, READ, Includes timeline, FAQ and distribution linkes for Veklury!

  • “October 1, 2020: Updated EUA released; USG oversight of the allocation and distribution of Veklury (remdesivir) is no longer required as supply is greater than demand by U.S. hospitals….”
  • About the Agreement with Gilead Science, Inc. and AmerisourceBergen (the sole distributor for remdesivir) – ARCHIVE [FYI these drug wholesaler merged in 2001 – REF]
October 1, 2020 Remdesivir for the Commercial Marketplace FAQs
Drug Pricing – ARCHIVE

October 3, 2020 – The Lancet correspondence: Remdesivir and COVID-19 – READ

September 16, 2020 – Infectious Diseases Society of America (IDSA) | COVID-19 Real-Time Learning Network – curated review of key information and literature about Remdesivir [cites research studies]- ARCHIVE

  • IDSA funded by CDC grant number 6 NU50CK000477-04-01
    • American Hostital Association (AHA LLN) funded by same grant CDC grant number 6 NU50CK000477-04-01 – REF
    • CDC grant also for serological, antigen and molecular diagnostic testing studies – REF
  • August 21, 2020 – Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients With Moderate COVID-19: A Randomized Clinical Trial – Spinner et al – READ
  • May 22, 2020 – NEJM (Preprint): Remdesivir for the Treatment of Covid-19 — Final Report by Beigel et al ACTT-1 Study Group Members – READ (Adaptive COVID-19 Treatment Trial (ACTT): An NIH-sponsored randomized, double-blind, placebo-controlled adaptive trial – TRIAL)
    • Trial protocol CHANGED mid trial! Originally had “death” on thier “7-point ordinal scale ” for primary outcome measure (Feb 21, 2020) – ARCHIVE, by April 27, 2020 they changed the trial design to be only “Time to recovery” as primary outcome measure – ARCHIVE [See Feb 21, 2020 below for screenshots]
  • May 27, 2020 – SIMPLE-Severe Trial: Gilead-sponsored multinational, open-label trial of remdesivir in patients with severe COVID-19 – NEJM: Remdesivir for 5 or 10 Days in Patients with Severe Covid-19 by Goldman et al – READ, Clinical Trial protocol (Dec 31, 2019) – READ
  • April 29, 2020 – The Lancet: Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial – Wang et al – READ, ARCHIVE – In China “Due to under-enrollment, the trial was stopped early and was likely under-powered.”
  • Other Remdesivir clinical trials – SEARCH, ARCHIVE

September 11, 2020 – HHS | Office of the Assistant Secretary for Preparedness and Response (ASPR): Update and Guidance on U.S . Government Allocation and Distribution of Remdesivir – Unclassified – SLIDES, ARCHIVE

  • US govt received 940,000 “vials” DONATED by Gilead, HHS purchases 500,000 “treatment courses” from July-Sept 2020 – at 6.25 vials/ave course = 3,125,000 vials+ – SLIDE 6, As of Sept 10, 2020 the HHS has allocated 76,644 cases (3,065,760 vials or 490,522 treatment courses) -see Slide 10
  • Hospitals report data into “HHS Protect” (SLIDE 11) – “HHS Protect is a secure decision-making and operations platform for the whole-of-government response to the COVID-19 pandemic.” – PDF
Product initially donated! Slide 3 – ARCHIVE
5 to 10-day course of remdesivir! – slide 4 – ARCHIVE

August 28, 2020 – PRESS RELEASE: Gilead’s Investigational Antiviral Veklury® (Remdesivir) Receives U.S. Food and Drug Administration Emergency Use Authorization for the Treatment of Patients With Moderate COVID-19 – Expands Previous Authorization of Veklury to Treat Hospitalized Patients with COVID-19 Regardless of Oxygen Status – READ, old READ

  • A “submission of a New Drug Application (NDA) to the FDA for remdesivir under the name Veklury®”
  • The Emergency use “authorization is temporary and may be revoked, and does not take the place of the formal new drug application submission, review and approval process.”

August 13, 2020- Clin. Epid. & Global Heath: Remdesivir and its antiviral activity against COVID-19: A systematic review – READ

July 10, 2020 – Nature Medicine: Extrapulmonary manifestations of COVID-19 – READ, WATCH

  • These are all side effects of remdesivir, yet the study concludes they are attributed to the virus SARS-CoV-2:

    “Although COVID-19 is most well known for causing substantial respiratory pathology, it can also result in several extrapulmonary manifestations. These conditions include thrombotic complications, myocardial dysfunction and arrhythmia, acute coronary syndromes, acute kidney injury, gastrointestinal symptoms, hepatocellular injury, hyperglycemia and ketosis, neurologic illnesses, ocular symptoms, and dermatologic complications.”

June 30, 2020 – Case report study of the first five COVID-19 patients treated with remdesivir in France (the remdesivir treatment was interrupted in 4 out of 5 patients) – READ, WATCH

June 30, 2020 – The Guardian: US secures world stock of key Covid-19 drug remdesivir – No other country will be able to buy remdesivir, … – READ, CREDIT

June 28, 2020 – HHS signed a memorandum of agreement with Gilead Sciences, Inc – READ, SOURCE

June 11, 2020 – NEJM – Compassionate Use of Remdesivir for Patients with Severe COVID-19 (study by Gilead 10 days of drug of which 60% patients reported adverse events including acute kidney failure) – READ, WATCH

May 28, 2020 – The Lancet – Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial by Wang et al – READ, PDF, (note this was in preprint April 29, 2020), Dr Alexander – SUBSTACK

  • “In adult patients admitted to hospital for severe COVID-19, “remdesivir was not associated with statistically significant clinical benefits.”
  • Furthermore, and very alarmingly, adverse events were reported in “102 (66%) of 155 remdesivir recipients versus 50 (64%) of 78 placebo recipients.” –REF

May 27, 2020 – NEJM: Remdesivir for 5 or 10 Days in Patients with Severe Covid-19 by Goldman et al – READ

  • SIMPLE-Severe Trial: Gilead-sponsored multinational, open-label trial of remdesivir in patients with severe COVID-19 – SOURCE

May 26, 2020 – MedRxiv Preprint: Remdesivir use in patients with coronavirus COVID-19 disease: a systematic review and meta-analysis of the Chinese Lancet trial with the NIH trial – by Paul Alexander et al – READ, CREDIT

  • Dr Alexander “when working for the World Health Organization (WHO) and the Pan American Health Organiization in Washington DC, published a paper in May 2020 that served to promote the use of Remdesivir. It was simply a review of 2 clinical trials that claimed a reduction in time to recovery and reduced risk of Serious Adverse Events” – REF

May 16, 2020 – The Lancet: Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial – Wang et al (China study of remdesivir) – READ, CREDIT

  • “No patients were enrolled after March 12 [2020], because of the control of the outbreak in Wuhan and on the basis of the termination criteria specified in the protocol, the data safety and monitoring board recommended that the study be terminated and data analysed on March 29.”
  • Remdesivir was stopped early because of adverse events in 18 (12%) patients versus four (5%) patients who stopped placebo early.” …[A]dverse events including gastrointestinal symptoms (anorexia, nausea, and vomiting), aminotransferase or bilirubin increases, and worsened cardiopulmonary status.

May 14, 2020 – Bloomberg: All eyes on Gilead – READ, ARCHIVE, Wikipedia – CREDIT, Comments from “Ken Kent, Gilead’s vice president in charge of chemical development and manufacturing…”

  • “In mid-January [2020], Kent got a call from Reza Oliyai, senior vice president for Gilead’s pharmaceutical operations, telling him the company would need to make large quantities of remdesivir to fight the novel coronavirus.”
  • “Remdesivir is tricky to produce—the monthslong process involves 70 raw materials, reagents, and catalysts”… and approximately “25 chemical steps in the production process. Most drugs require about half that number. Some of the steps are more delicate than others. An early one uses a reagent so flammable it will spontaneously combust if exposed to air. Another involves a poison called trimethylsilyl cyanide.” – REF
    • Symptoms of cyanide poisoning includes kidney failure, the same symptom remdesivir recipients often experience!
  • “The original end-to-end manufacturing process required 9 to 12 months to go from raw materials at contract manufacturers to finished product, but after restarting production in January 2020, Gilead Sciences was able to find ways to reduce the production time to six months” – REF

May 7, 2020 – Japan approves Gilead Sciences’ remdesivir as COVID-19 drug – READ

May 7, 2020 – PRESS RELEASE: Gilead Announces Approval of Veklury® (remdesivir) in Japan for Patients With Severe COVID-19 – READ, ARCHIVE

May 4, 2020 – Dr Shiva Ayyadurai: Dr.SHIVA LIVE: The Truth About Remdesivir & Immune Health. A CytoSolve Analysis – presentation on viruses, the immune system and remdesivir – WATCH, What is Cytosolve? – EXCERPT, FULL, BACKUP

  • Remdesivir triphosphate (RDV-TP) (Gilead # GS-441524) inhibits the viral enzyme RNA-dependent RNA Polymerase (RDRP) – it mimics Adenine. RDRP is necessary for viral RNA replication in cells
  • Gilead trial discussed – remdesivir – 71% (5 day tmt arm) and 74% (10 day tmt arm) people had ADVERSE EFFECTS!, [no placebo group], which included Acute Respiratory Failure & Liver dysfunction! – EXCERPT
Remdesivir has ONLY one Mechanism of Action – WATCH
WATCH, Microbiology notes – READ

May 1, 2020: FDA issued an Emergency Use Authorization (EUA) for the emergency use of Veklury® (remdesivir) for treatment of hospitalized patients with severe 2019 coronavirus disease (COVID-19) – PDF, ARCHIVES, Remdesivir – FDA

  • On January 21, 2022 – the EUA was REVOKED

April 30, 2020 – The Highwire Ep 161: CORONAVIRUS: A NATION DIVIDED – segment on Chloroquine vs. Remdesivir – WATCH, FULL

April 29, 2020 – Time Magazine: Remdesivir Receives FDA Emergency Use Authorization After Promising Results as a Coronavirus Treatment – READ

April 29, 2020 – NY Post: Dr. Fauci praises remdesivir after breakthrough in coronavirus treatment – WATCH & READ, In the Whitehouse – EXCERPT

  • “reduced coronavirus recovery time” – [the trial was not complete and the endpoint were changed after the trial was set]

April 29, 2020 – NY Post: Gilead says remdesivir shows ‘positive’ signs for coronavirus treatment – READ

  • The firm teased an upcoming briefing by NIAID [Dr Fauci] that would offer “detailed information” about the results.
  • “The company also announced its own study showed that 62% of patients treated early with remdesivir were discharged from the hospital, compared with 49% of patients who were treated late.”

April 29, 2020 – LA Times: Clinical trial of remdesivir may be a turning point in coronavirus fight – READ

  • Government researches suggest antiviral medication remdesivir helped patients with advanced COVID-19 recover 31% faster than a placebo treatment. – 1,063 patients enrolled in trial
  • “The early results, emerging from a large clinical trial sponsored by the National Institute of Allergy and Infectious Diseases, appears to position the drug as the standard therapy for hospitalized COVID-19 patients going forward.”
  • “the benefits were so clear that researchers halted this portion of the trial early. As they move on to investigate other drugs against COVID-19, researchers will give all trial participants remdesivir and will make the antiviral the new standard against which other drugs are compared, Fauci said.”
  • [Dr Marik comments the trial was fraudulentWATCH]
  • China study with remdesivir found “no significant difference in how sick patients became or how quickly they recovered” – The Lancet – STUDY

“What [the clinical trial] has proven is that a drug can block this virus,”“This drug happens to be blocking an enzyme that the virus uses.”

Fauci said on Wednesday in the Oval Office of the White House

April 29, 2020 – Gilead PRESS RELEASE – Gilead Sciences Statement on Positive Data Emerging From National Institute of Allergy and Infectious Diseases’ Study of Investigational Antiviral Remdesivir for COVID-19 – READ, ARCHIVE

April 29, 2020 – Gilead PRESS RELEASE – Gilead Announces Results From Phase 3 Trial of Investigational Antiviral Remdesivir in Patients With Severe COVID-19 – Study Demonstrates Similar Efficacy with 5- and 10-Day Dosing Durations of Remdesivir – READ, ARCHIVE

April 29, 2020 – The Lancet: Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial – Wang et al (CHINA) – READ, LA Times – ARTICLE

  • Hospitalised patients – 158 received remdesivir (GS-5734) and 79 placebo
  • the found “no significant difference in how sick patients became or how quickly they recovered” – ARTICLE
    [Yet the same day this was published Fauci announced remdesivir as the standard of care for COVID-19 in hospitals in the US]
  • Adverse events were reported in 102 (66%) of 155 remdesivir recipients versus 50 (64%) of 78 placebo recipients. Remdesivir was stopped early because of adverse events in 18 (12%) patients versus four (5%) patients who stopped placebo early.”
  • [Note LA Times claimed remdesivir was “used effectively against Ebola” this is untrue, it was pulled from the ebola trials, it was increasing mortality!- ARTICLE]

April 26, 2020 – COVID-19 Early Treatment Fund: Entrepreneur and philanthropist Steve Kirsch founded CETF to fund outpatient clinical trials of repurposed drugs – Website first ARCHIVED, READ,

  • “This site describes the fastest way to defeat the virus.” Early treatment FAQ – READ
  • Remdesivir was top of the list! – ARCHIVE
  • Clinical Trials @ Aug 2020 – ARCHIVE, now – READ

April 24, 2020 – CNBC: Coronavirus: Remdesivir had no effect on patients, according to leaked Gilead study on using Remdesivir to treat Covid-19 – Hannah Kuckler, Financial Times – WATCH, CREDIT

  • WHO allegedly prematurely published results from the first RCT on Remdesivir conducted in China where 237 patients were enrolled of which 158 were given remdesivir (the study planned to enrol 453 but fell short!). Mortality at 28 days was 13.9% drug, 12.8% placebo control
  • But Gilead believe the WHO’s post had ‘inappropriate characterization of the study’
  • Note on Feb 2, 2020 – 50 Tons of Vitamin C was trucked into Wuhan for healthcare workers etc, and even IV vit C trials couldn’t enrol enough patients – HERE

April 21, 2020 – Defense Visual Information Distribution Service: Fort Detrick Installation Utilizes Whole of Government Approach to Tackle COVID-19 – READ, CREDIT

  • “While USAMRDC scientists hope to have a vaccine available within 12-18 months, they are also utilizing their extensive laboratory capabilities to rapidly advance COVID-19 antiviral treatments. The U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID), located on Fort Detrick, has consistently been at the forefront of the discovery and development of biodefense therapeutics, including remdesivir, mAB114 and ZMapp, which were used during the 2018-2020 Ebola virus disease outbreak in the Democratic Republic of Congo” [so they knew remdesivir’s high mortality rate]

April 19, 2020 – In Jan & Feb 2020 remdesivir trials for COVID-19 were conducted, on April 19, 2020 the last patient was enrolled in the NIH trial according to Dr Marik. Ten days later (April 29, 2020), before the study had terminated, Dr Fauci announced in the oval office the trial was “good news”! – WATCH

April 19, 2020 – Microbiology Notes: Remdesivir- Mechanism of Action, Uses, Synthesis & COVID-19 – ARCHIVE, Dr Shiva – CREDIT, Mode of Action – IMAGE

April 17, 2020 – NIH: Antiviral remdesivir prevents disease progression in monkeys with COVID-19 – Study supports clinical testing under way across U.S. – READ, CREDIT

April 15, 2020 – PRESS RELEASE: Gilead Provides Additional Information Regarding 2020 Annual Meeting of Stockholders Due to COVID-19 Precautions – READ, ARCHIVE

April 11, 2020 – Infectious Disease Society: Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 – ARCHIVE

  • “The guideline panel suggests against remdesivir for routine treatment of patients with oxygen saturation >94% and no supplemental oxygen; however, strongly urges continued study through recruitment into RCTs”
    • The mode of action of remdesivir is only “acts by causing premature termination of viral RNA transcription” – [is viral replication even an issue in this stage of disease progression in hospitalised patients? Especially given the drugs “toxicity profile”.]
  • “Patients receiving five days of remdesivir may experience fewer SAEs and adverse events leading to treatment discontinuation than patients receiving 10 days of remdesivir…”
Why is remdesivir considered for treatment? – source

April 10, 2020 – NEJM: Compassionate Use of Remdesivir for Patients with Severe Covid-19 – Grein et al (Gilead Sciences) – PDF

April 9, 2020 – Quartz: How the military secured a coronavirus drug that has yet to win FDA approval – READ, CREDIT

  • “News of the military’s deal with Gilead was surprising, shining a light on the military’s unique ability to acquire medications before the FDA has signed off on the same drug for average Americans, if it ever does.””

April 8, 2020 – PRESS RELEASE: Gilead Announces $20 Million Philanthropic Fund to Support Nonprofit Organizations Impacted by the COVID-19 Crisis – READ, ARCHIVE

  • “Gilead Sciences, Inc. (Nasdaq: GILD) announced the creation of the global Gilead CARES (COVID-19 Acute Relief and Emergency Support) Grantee Fund to provide financial support to current grantees facing an imminent closure or termination of vital services due to losses attributable to the COVID-19 pandemic. The fund will provide up to $20 million in donations to these nonprofit groups.”

April 5, 2020 – Motley Fool: Gilead Has Treated More Than 1,700 COVID-19 Patients With Remdesivir – READ

March 25, 2020 – National Center for Global Health & Medicine (Japan): NCGM Fights against COVID-19 – Lessons Learned (2nd Edition) – PDF, CREDIT, NCGM – HERE, ARCHIVE

  • Reported investigator-initiated clinical trials were launched using Remdesivir, as part of “multi-regional clinical trials in collaboration with the NIH (National Institutes of Health, USA)”.

March 23, 2020 – NY Times: Coronavirus Patients in Limbo as Gilead Suspends Emergency Drug Access – ARCHIVE

March 18, 2020 – STAT News: WHO to launch multinational trial to jumpstart search for coronavirus drugs – READ, CREDIT

  • SOLIDARITY trial “…a multiarm, multicountry clinical trial for potential coronavirus therapies, part of an aggressive effort to jumpstart the global search for drugs to treat Covid-19.
  • “The drugs to be tested are the antiviral drug remdesivir; a combination of two HIV drugs, lopinavir and ritonavir; lopinavir and ritonavir plus interferon beta; and the antimalarial drug chloroquine.

March 16, 2020 – STAT News: As the coronavirus spreads, a drug that once raised the world’s hopes is given a second shot – READ, CREDIT

March 11, 2020 – Military Times: Army signs agreement with drug giant Gilead on experimental COVID-19 treatment – READ

March 11, 2020 – U.S. Army Medical Materiel Development Activity: USAMMDA Announces Agreement with Gilead Sciences to Provide Investigational New Drug for Warfighters Exposed to Coronavirus Disease – READ, CREDIT

  • USAMMDA, a subordinate command of the U.S. Army Medical Research and Development Command, announced ” it has entered into a Cooperative Research and Development Agreement [CRADA] with Gilead Sciences to provide Gilead’s investigational drug, remdesivir, for the treatment of Department of Defense personnel exposed to coronavirus disease 2019, known as COVID-19.”
  • “In the CRADA, the USAMMDA Force Health Protection program will allow for the investigational use of remdesivir provided by Gilead, at no cost to the government, in the absence of any approved treatment options”
  • Today’s announcement builds on a longstanding partnership between the DOD and Gilead Sciences to protect our Service Members….Gilead continues to test a collection of their antiviral molecules and remdesivir against other viral pathogens representing potential global health threats.

March 5, 2020 – US Department of Defense: Defense Department Press Briefing Investigating and Developing Vaccine Candidates Against COVID-19 – READ, CREDIT

  • Army Brig. Gen. Michael J. Talley, commanding general of U.S. Army Medical Research and Development Command (USAMRDC) and Fort Detrick, revealed that “a cooperative research and development agreement with an industry partner is under review for the DOD to gain access to an antiviral drug for treatment use in our medical centers, our military treatment facilities.”

March 5, 2020 – NEJM: First Case of 2019 Novel Coronavirus in the United States – Holshue et al – READ

February 28, 2020 – Scientific America: A Promising Antiviral Is Being Tested for the Coronavirus—but Results Are Not Yet Out – READ, ARCHIVE

  • The drug remdesivir is effective against many other viruses, and some experts are optimistic that it—or similar compounds—may work for the pathogen responsible for COVID-19
  • …”and a malaria drug called chloroquine, which is not an antiviral but has shown some efficacy against COVID-19 in a lab dish. Yet experts say drugs that specifically target other pathogens are unlikely to work well enough.”
  • Timothy Patrick Sheahan, an assistant professor of epidemiology at the University of North Carolina Gillings School of Global Public Health, is among those in the U.S. working on antiviral drugs for COVID-19. Like De Clercq, he is skeptical that many of the antivirals already on the market would work.

I’m doubtful that existing approved medications for other infectious diseases will have some magical property against this new coronavirus,”

Tim Sheahan
  • [Note Sheahan has a conflict of interest in making this statement as he helped develop remdesivir otherwise known as GS-5734 ]
  • “Sheahan and his colleagues have published several papers showing that remdesivir is effective against SARS, MERS and related bat coronaviruses, as well as some of the common cold coronaviruses.” – HERE & HERE
  • “Lisa Gralinski, an assistant professor of epidemiology and colleague of Sheahan’s at the Gillings School,
  • I think it will probably be really effective” if you can get it to the patient within the first or second week… But “you’re not going to be able to come in and give this drug to someone who’s approaching end-stage lung disease and improve their outcome.” At that point, the lung damage is no longer being caused by viral replication but is happening because of the body’s own immune response—so an antiviral would likely not be effective. Yet if enough of the drug is available, Gralinski says, she would give it at the time of diagnosis.”
  • “…if we already have something that’s mostly through development, like has luckily been the case with remdesivir, you can get it to people very rapidly.” Even if the drug proves to be effective, however, producing enough of it and distributing it to everyone in need is not guaranteed.”

February 26, 2020 – Senator Rand Paul’s wife Kelley buys stocks in Gilead – SOURCE

February 26, 2020 – PRESS RELEASE: Gilead Sciences Initiates Two Phase 3 Studies of Investigational Antiviral Remdesivir for the Treatment of COVID-19 – READ, ARCHIVE

  • “Gilead’s trials will evaluate two dosing durations of the drug, which is given intravenously. The randomized, open-label, multicenter studies will enroll about 1,000 patients mostly in Asia, as well as in countries that have had high numbers of diagnosed cases. The trials are planned to start in March.
  • These trials are on top of two clinical trials in China’s Hubei province led by the China-Japan Friendship Hospital and a recently launched trial in the U.S. led by the NIAID. Gilead donated the drug and provided scientific expertise for those trials. The China trial data is expected in April.” – REF
  • “despite its deadly history – [remdesivir is] approved for use in clinical trials to evaluate its efficacy in the treatment of COVID-19. – READ

February 25, 2020 – NIAID: NIH Clinical Trial of Remdesivir to Treat COVID-19 Begins – Study Enrolling Hospitalized Adults with COVID-19 in Nebraska – READ, ARCHIVE

  • Clinical Trial begun at the University of Nebraska Medical Center (UNMC) in Omaha – sponsored by NIAID – Clinical Trial NCT04280705 – HERE
  • UNMC’s National Quarantine Unit is supported by the office of the Assistant Secretary for Preparedness and Response (ASPR) at the Department of Health and Human Services. It has a 20-bed capacity and is in close proximity to the Nebraska Biocontainment Unit, should a higher level of care be needed. Clinical trial participants are cared for in the biocontainment unit.”

February 21, 2020ClinicalTrials.gov: Adaptive COVID-19 Treatment Trial – READ, ARCHIVE, That trial will be conducted at up to 50 sites around the world and will test remdesivir against a placebo. – SOURCE

  • April 27, 2020 – NIAID changed clinical trial trial Primary Outcome Measure, to time to recovery and removing “death” from the criteria – ARCHIVE
February 25, 2020 – source
April 27, 2020 – source

February 18, 2020 – Gilead Sciences Update On The Company’s Ongoing Response To COVID-19ARCHIVE, LIVE, All ARCHIVES

  • “Remdesivir is an investigational nucleotide analog with broad-spectrum antiviral activity – it is not approved anywhere globally for any use.”
  • “This is an experimental medicine that has only been used in a small number of patients with COVID-19 to date, so Gilead does not have an appropriately robust understanding of the effect of this drug to warrant broad use at this time.”
  • “Remdesivir has demonstrated in vitro and in vivo activity in animal models against the viral pathogens MERS and SARS, which are also coronaviruses and are structurally similar to COVID-19.” [so to did cheap Hydroxychloroquine, with a history and safety profile]
  • To date “two studies are being coordinated by the China-Japan Friendship Hospital and are being conducted at multiple sites in Hubei province” China.
    • The study in patients with severe disease began enrolling patients on February 6, 2020 – TRIAL
    • The study in patients with moderate disease began enrolling patients on February 13, 2020

February 6, 2020 – ClinicalTrails. gov: Severe 2019-nCoV Remdesivir RCT – READ, ARCHIVE, SOURCE

February 6, 2020 – New York Times: China Begins Testing an Antiviral Drug [remdesivir] in Coronavirus Patients – READ

February 5, 2020 – ClinicalTrails. gov: Mild/Moderate 2019-nCoV Remdesivir RCT – READ, ARCHIVE

February 5, 2020 – Washington Times: Chinese scientists ask for patent on U.S. drug to fight virus – READ
Gilead, headquartered in Foster City, California, said it applied in 2016 for a Chinese patent on use of remdesivir against coronaviruses and is waiting for a decision.

January 31, 2020 – Gilead Sciences Statement on the Company’s Ongoing Response to the 2019 Novel Coronavirus (2019-nCoV) – READ, READ, CREDIT

  • “While there are no antiviral data for remdesivir that show activity against 2019-nCoV at this time, available data in other coronaviruses give us hope. Remdesivir has demonstrated in vitro and in vivo activity in animal models against the viral pathogens MERS and SARS, which are coronaviruses that are structurally similar to 2019-nCoV. There are also limited clinical data available from the emergency use of remdesivir in the treatment of patients with Ebola virus infection.”
  • Gilead is working closely with global health authorities..through the appropriate experimental use of our investigational compound remdesivir.:
    • U.S. Food and Drug Administration (FDA),
    • the U.S. Centers for Disease Control and Prevention (CDC), the U.S. Department of Health and Human Services (DHHS),
    • the U.S. Department of Defense (DoD) – CBRN Medical,
    • the China CDC and National Medical Product Administration (NMPA),
    • the World Health Organization (WHO),
    • and the U.S. National Institute of Allergies and Infectious Diseases (NIAID), and
    • along with individual researchers and clinicians

January 21, 2020 – The antiviral Remdesivir was used on the first COVID-19 patient in the US, given on the evening of day 7 of hospitalisation – TIMELINE, Daoyu15 Substack: Study of the USA-WA-1 case report… – READ, Also – READ

  • But the patient had cleared the virus by day 3 of hospitalisation (as indicated by higher PCR cycles needed indicating viral titers dropped) and when pneumonia began to develop on the 6th day of hospitalization, was subjected to antibiotics treatment – REF
  • Remdesivir given evening of hospitalisation day 7 at the same time the antibiotic Vancomycin was stopped, the next day the patient “clinical conditions improved”. Remdesivir was used after the virus had cleared! and used in conjunction with other treatments, yet this case study was justification for clinical trials!

January 2020 – “In mid-January, [Ken] Kent got a call from Reza Oliyai, senior vice president for Gilead’s pharmaceutical operations, telling him the company would need to make large quantities of remdesivir to fight the novel coronavirus.” – REF

2019

December 31, 2019 – Clinical Trials.gov | Gilead Sciences-sponsored : Study to Evaluate the Safety and Antiviral Activity of Remdesivir (GS-5734™) in Participants With Severe Coronavirus Disease (COVID-19)READ, ARCHIVE March 3, 2020 (Phase 3 Not yet recruiting) – ARCHIVE, Protocol – PDF, History of initial study changes – ARCHIVE

  • May 27, 2020 – SIMPLE-Severe Trial: Gilead-sponsored multinational, open-label trial of remdesivir in patients with severe COVID-19 – NEJM: Remdesivir for 5 or 10 Days in Patients with Severe Covid-19 by Goldman et al – READ, SOURCE

December 24, 2019 – [Bloomberg: All eyes on Gilead – REF] – Tomas Cihlar, VP for discovery virology at Gilead Sciences Inc., received a email from a top infectious diseases expert at the University of Virginia.

  • “There were cases of pneumonia suddenly emerging in Wuhan, China. Watch this one, the virologist warned. It might be a new coronavirus.”
  • “Remdesivir was one of the few experimental medicines that had shown promise in lab studies against a wide variety of coronaviruses.” [i.e. in vitro like Chloroquine in 2005]
  • Gilead started planning “on the assumption” the new virus would turn into a pandemic…”Within weeks, Chief Executive Officer Daniel O’Day formed a task force to study how to test remdesivir and, if it worked, mass-produce it”

December 12, 2019 – NEJM: A Randomized, Controlled Trial of Ebola Virus Disease Therapeutics – (monoclonal antibodies vs remdesivir), funded by NIAID. [The study showed 28 days of remdesivir increased mortality of 53.1% and pulled from the trial] – READ, PDF, WATCH, Dr Marik comments – WATCH,

  • Remdesivir dropped from Ebola trial in DRC – increased risk of death & kidney failure- TIMELINE

November 27, 2019 – NEJM: A Randomized, Controlled Trial of Ebola Virus Disease Therapeutics – Malangu et al (PALM Consortium Study Team) – READ in Democratic Republic of Congo, ClinicalTrials.gov number NCT0371958

  • November 27, 2019 – NIAID: Investigational Drugs Reduce Risk of Death from Ebola Virus Disease
    Study Leaders Publish Results from NIH-DRC-WHO Clinical Trial of Four Experimental Therapies – READ, ARCHIVE
  • The clinical trial known as PALM, short for “Pamoja Tulinde Maisha,” a Kiswahili phrase that translates to “together save lives,” was organized by an international research consortium coordinated by the World Health Organization (WHO).
  • “The mortality rate in the remdesivir treatment group, 53% (93/175), was similar to ZMapp” the highest mortality rate of all investigational drugs
Table 2 – remdesivir with highest mortality – source

September 2019 – Antiviral Research: Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase – Brown with Baric & Sheahan et al – READ, SOURCE

August 13, 2019 – Clinical Trials Arena: Preliminary findings from the Pamoja Tulinde Maisha (PALM) clinical trial have revealed that two monoclonal antibodies, REGN-EB3 and mAb114, produced a higher chance of survival in Ebola patients. (not remdesivir) – READ

  • “Reuters noted that around 29% of subjects treated with REGN-EB3 and 34% in the mAb-114 arm died, compared to 49% of those on ZMapp and 53% who received remdesivir.”

August 12, 2019 – Science: Finally, some good news about Ebola: Two new treatments dramatically lower the death rate in a trial (not remdesivir!) – READ

August 12, 2019 – NIH: Independent Monitoring Board Recommends Early Termination of Ebola Therapeutics Trial in DRC Because of Favorable Results with Two of Four Candidates – Pamoja Tulinde Maisha (PALM) study – ARCHIVE

  • The “study leaders halted the trial early, on August 9, 2019, as recommended by an independent data and safety monitoring board based on its review of preliminary data from 499 study patients.” – REF

August 9, 2019 – Remdesivir dropped from Ebola trial – TIMELINE

2018

March 6, 2018 – American Society of Microbiology: Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease – Agostini, with Baric & Sheahan et al – READ, SOURCE

2017

August 31, 2017 – Gillings School researchers receive $6M+ grant to fight infectious diseases – (Ralph Baric) – READ

  • “In previous studies, Baric, Sheahan and colleagues found that GS-5734 prevents the development of severe acute respiratory syndrome coronavirus (SARS-CoV) in mice. The drug also was shown to inhibit MERS-CoV and multiple other coronaviruses (CoV), suggesting that it may actually inhibit all CoV.”
  • Ralph S. Baric, PhD, professor, and Timothy Sheahan, PhD, research assistant professor, both in the Department of Epidemiology at the Gillings School

August 9, 2017 – NIH GRANT: Broad-spectrum antiviral GS-5734 to treat MERS-CoV and related emerging CoV – Baric & Sheahan – READ, CREDIT

  • Awarded Up to $6M multiple Grants – READ

August 8, 2017 – US Patent #9,724,360 : Methods for treating Filoviridae virus infectionsREAD, CREDIT

  • “Provided are compounds, methods, and pharmaceutical compositions for treating Filoviridae virus infections by administering ribosides, riboside phosphates and prodrugs thereof, of Formula IV: ##STR00001## The compounds, compositions, and methods provided are particularly useful for the treatment of Marburg virus, Ebola virus and Cueva virus infections.”

History of Gilead Sciences – LINK

2016

2016 – Warren, T., et al., (2016), “Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys“, Nature, 531:381-5. – READ, Patent – CREDIT

  • “The 2013–2016 outbreak of [Ebola virus (EBOV) disease] EVD in West Africa was the largest and most complex EBOV outbreak in the recorded history of the disease”…”No antiviral therapeutics have yet received regulatory approval or demonstrated clinical efficacy” for Ebola
  • “Here we report the discovery of a novel small molecule GS-5734, a monophosphoramidate prodrug of an adenosine analogue, with antiviral activity against EBOV. GS-5734 exhibits antiviral activity against multiple variants of EBOV and other filoviruses in cell-based assays”
  • The broad-spectrum antiviral activity of GS-5734 in vitro against other pathogenic RNA viruses, including filoviruses, arenaviruses, and coronaviruses, suggests the potential for wider medical use.”

1999

October 1999- Gilead and Roche announced that the FDA approved Tamiflu for the treatment of influenza A and B in adults – in time for the 1999-2000 flu season in the US. – ARCHIVE, ARCHIVE

  • Tamiflu™ (oseltamivir phosphate) is the first flu pill from a new class of drugs called neuraminidase inhibitors that are designed to be active against all common strains of the influenza virus.
  • Then in November 2000, Tamiflu was approved for the prevention of naturally occurring influenza A and B in adults and adolescents 13 years and older. In addition to the United States, Tamiflu is available in 26 countries worldwide.
  • Some of the side effects from Tamiflu include suicide! “Sadly and predictably, using Tamiflu for treating the common flu will tend to increase the chances of creating super-viruses that will become immune to anti-viral drugs. It is almost as though this drug has the capacity to create thousands (or millions) of “terrorist cells” that could threaten the body (and the body politic).” – (2010 – How to create your own pandemic) READ

1997

1997 – Gilead and Roche announce positive Phase II results from a study of its influenza compound, GS 4104. In time will be called Tamiflu™ (oseltamivir phosphate)

1997 – Gilead names Donald H. Rumsfeld Chairman of Gilead Sciences Board of Directors, succeeding Michael L. Riordan, MD, former Chairman and President, and Gilead founder – REF, ARCHIVE, WIKI, CREDIT

  • Rumsfeld remained chariman until 2001.
  • Rumsfeld was appointed secretary of defense for a second time in January 2001 by President George W. Bush.
  • September 10, 2001, the day before 9/11 attack – Donald Rumsfeld declared “We cannot track 2.3 TRILLION dollars” – WATCH

1996

1996 – Gilead’s receives FDA approval for it’s first commercial product, VISTIDE® (cidofovir injection), for the treatment of cytomegalovirus (CMV) retinitis in patients with AIDS. – REF

  • Gilead ships VISTIDE to wholesaler and specialty distributors nationwide within hours of approval. VISTIDE is marketed in the United States by Gilead’s special sales force of Antiviral Specialists. – REF
  • By 1997 is is available in both the United States (marketed by Gilead) and abroad (marketed by Pharmacia & Upjohn)

1996 – “Gilead and Hoffmann La-Roche agree to develop and market therapies to treat and prevent viral influenza. – REF

  • Roche agrees to pay Gilead up to $50 million in milestone and licensing fees in exchange for worldwide rights to Gilead’s proprietary anti-influenza technology; Roche also funds development costs.
  • Gilead announces the discovery of an orally active, highly potent compound that inhibits the replication of the influenza virus. Preclinical studies demonstrate promising antiviral activity against multiple strains of the influenza virus.”

1990

July 1990 – Gilead and Glaxo Wellcome form a five-year collaborative research agreement under which Gilead will conduct research with a goal of identifying code blocker compounds with potential application in the diagnosis, prevention and treatment of cancer.” – REF

1987

1987 – Gilead company is formed – ARCHIVE

  • “Gilead is founded by Michael Riordan, MD. Our name was derived from an ancient region in the Middle East, presently part of the nation of Jordan. This region was recognized in antiquity as the source of a healing compound known as the “balm of Gilead.””

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Dr Richard Bartlett https://totalityofevidence.com/dr-richard-bartlett/ Tue, 08 Mar 2022 09:38:25 +0000 https://totalityofevidence.com/?p=2724 Dr Richard Bartlett is a West Texas frontline doctor with over 28 years experience as an emergency room physician, who in March 2020 found a cheap and effective treatment for breathing issues associated with COVID-19, which has since been corroborated…

The post Dr Richard Bartlett first appeared on Totality of Evidence.

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Dr Richard Bartlett is a West Texas frontline doctor with over 28 years experience as an emergency room physician, who in March 2020 found a cheap and effective treatment for breathing issues associated with COVID-19, which has since been corroborated through clinical trails at Oxford University.

Budesonide is a generic, cheap, corticosteriod which is used as a nebulised treatment to relieve COVID-19 breathing issues. Dr Bartlett says that for years it has been safely used on premature babies right up to frail elderly. Nebulisers make a “mist out of medicines” that you breath in, important when you can’t take a deep breath, which is what makes it different to an inhaler.

Dr Richard Bartlett
  • Budesonide Works website – HERE
  • Budesonide for COVID-19 – HERE

Following are a few of Dr Bartlett’s interviews that trace his early pandemic journey from the front lines.

Interviews in reverse chronological order

2023

July 27, 2023 – The White Coat Summit | The Reckoning: Freedom Over Medical Tyranny by Dr. Richard Bartlett – WATCH

May 11, 2023 – The Highwire Ep 319: Awakening – Dr Richard Bartlett is back – ‘SILVER BULLET’ PROTOCOL FOR COVID VALIDATED TWO YEARS AFTER ATTACKED – WATCH, FULL

The protocol worked but absolutely it’s a bioweapon, absolutely it was not natural…there’s no confusion, this is not a normal virus…

Dr Richard Bartlett

“Fauci did not do a retraction on possibly the most dangerous misinformation that has ever been spoken on the planet when he shut down a treatment that would have prevented at least 90% of hospitalisations”

Dr Richard Bartlett

There was a point were the hospitals were over flowing but it could have all been prevented…

Dr Richard Bartlett

2022

March 8, 2022 – Daystar TV: Dr. Simone Gold | Dr. Peter McCullough | Dr. Richard Bartlett – @10min WATCH (estimated to have reached 1.7 billion views)

March 1, 2022 – Scott McKay speaks with Dr Bartlett – An overview of his budesonide journey @8min – WATCH, SOURCE

February, 2022 – Reawakening Tour: Dr. Bartlett shares his inspiration for his COVID treatment strategy – WATCH

January 7, 2022 – Mel K Show speaks with Dr Richard Bartlett on killing COVID fear – WATCH

2021

September 28, 2021 – Dr Ardis interviews Dr Bartlet – “The Oxford study showed 90% reduction in hospitalisation for people with COVID” – WATCH

September 3, 2021 – The Highwire Episode 231: Dr Bartlett shares his experience with the monoclonal antibody treatment – WATCH

June 2021? – The Dr Ardis Show with Dr Bartlett – WATCH

March 4, 2021 – The Highwire: “This could have saved 450,000 lives” say Dr Bartlett – WATCH

February 9, 2021 – Universitiy of Oxford: Common asthma treatment reduces need for hospitalisation in COVID-19 patients, study suggests – READ, ARCHIVE

  • The STOIC study found that inhaled budesonide given to patients with COVID-19 within seven days of the onset of symptoms also reduced recovery time.
  • Findings from the phase 2 randomised study, which was supported by the NIHR Oxford Biomedical Research Centre (BRC). “The findings from 146 people – of whom half took 800 micrograms of the medication twice a day and half were on usual care – suggests that inhaled budesonide reduced the relative risk of requiring urgent care or hospitalisation by 90% in the 28-day study period. Participants allocated the budesonide inhaler also had a quicker resolution of fever, symptoms and fewer persistent symptoms after 28 days.”

February 8, 2021 – PrePrint: Inhaled budesonide in the treatment of early COVID-19 illness: a randomised controlled trial – Ramakrishnan et al – READ, published April 9, 2021 in The Lancet – READ

2020

November 2020 – Joni Table Talk: COVID-19 Treatments with Dr Richard Bartlett – LISTEN

October 20, 2020 – Out of Shadows producer interviews Dr Bartlett: “ICU emptied in 48 hours once they used budesonide” – WATCH, ARCHIVE

October 15, 2020 – The Highwire: The asthma drug, COVID’s Silver Bullet? – WATCH

September 24, 2020 – Thrivetime Show: Dr. Richard Bartlett On the COVID-19 Therapy That Produces a 0% Fatality Rate – WATCH

September 14, 2020 – Daystar Christian TV Network: Dr. Richard Bartlett shared his successful treatment protocol for COVID-19 and the impact it is having – WATCH @15:45

August 1, 2020 – Drbeen Medical Lectures: Nebulized Steroids (Budesonide) Talk with Dr. Richard Bartlett – WATCH

July 28, 2020 – CBS7: Dr. Bartlett discusses COVID “cure” with Midland County leaders – The West Texas doctor who claims to have the “silver bullet” for COVID-19 was invited to speak at Monday’s Midland County Commissioners’ Court – WATCH

July 21, 2020 – EricMajors TV: Dr. Richard Bartlett on inhaled steroid Budesonide and Covid-19 – WATCH

July 20, 2020 – Australian Jewish Association: Dr Zelenko (New York) and Dr Bartlett (Texas) discuss their positive COVID-19 treatment outcomes – WATCH

July 20, 2020? – Debbie Georgatos of America, Can We Talk?:Congressman Dr. Ralph Abraham Delivers Dr. Richard Bartlett’s Cure For COVID-19 To President Trump. – WATCH

July 8, 2020 – CBS7: West Texas doctor goes viral with claim of COVID “cure” – Permian Basin medical leaders are pushing back against Dr. Richard Bartlett’s statements – WATCH

June 18, 2020 – CBS7 | Dr Bartletts Press Conference: West Texas doctor claims to have “silver bullet” for COVID-19 – The steroid-based treatment is not currently approved by the FDA – – WATCH

July 25, 2020- Forture: Is a new steroid treatment a miracle solution for COVID-19—or is it snake oil? – READ

  • Richard Bartlett made waves in a July 2 interview that already has racked up 4.1 million views online. …boasted a 100% survival rate for his patients since March by using his treatment strategy, centered around an inhaled steroid called budesonide.

July 16, 2020 – ACWT: Dr. Richard Bartlett and COVID Patient Stories – WATCH, ARCHIVE, YouTube

July 15, 2020 – Global Journal of Science Frontier Research: SARS-Cov-2 and the Case for Empirical Treatment – Watkins and Bartlett – READ, SOURCE, PDF, REF

July 13, 2020 – KCTV5 News – “Silver Bullet” against COVID-19 – WATCH

July 10, 2020 – News West 9 | Facts Not Fear: COVID patients defend Dr. Bartlett’s ‘silver bullet’ medicine regimen – WATCH

July 2, 2020 – America Can We Talk with Debbie Georgatos: Dr Richard Bartlett shared his “COVID cure” – WATCH, BACKUP, SOURCE, YouTube deleted ARCHIVE

June 23, 2020 – The Hacked Life with Joel Evan: The “Silver Bullet” For COVID-19 with Dr Richard Bartlett – LISTEN, SOURCE

May 23, 2020 – News West 9 | Facts Not Fear: Texas doctor believes he has found ‘silver bullet’ for COVID-19 – WATCH, CREDIT

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Dr Tess Lawrie https://totalityofevidence.com/dr-tess-lawrie/ Mon, 07 Mar 2022 09:17:53 +0000 https://totalityofevidence.com/?p=2553 Dr Tess Lawrie is a medical doctor and research consultant based in the UK. She is the CEO of Evidence-Based Medicine Consultancy (E-BMC Ltd.) and EbMC Squared, a founding member of the BiRD group, she sits on the steering committee…

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Dr Tess Lawrie is a medical doctor and research consultant based in the UK. She is the CEO of Evidence-Based Medicine Consultancy (E-BMC Ltd.) and EbMC Squared, a founding member of the BiRD group, she sits on the steering committee of the World Health Council and the Better Way Conference, and is part of the leadership for The Unity Project. Dr Lawrie is an external analyst for the WHO as a Guideline Methodologist – she assesses evidence, compiles it and makes recommendations. She is independent and has no conflicts of interest.

After hearing Dr Pierre Kory’s US senate testimony on December 8, 2020, Dr Lawrie took it upon herself to conducted a rapid systematic review and meta-analysis of all the scientific research referenced by FLCCC alliance on ivermectin and “was struck by the seeming efficacy of the drug in reducing mortality and morbidity [of COVID-19], and, as a doctor, considered it her duty to inform the UK health authorities about this potential breakthrough treatment.”

She has battled resistance since that time against the use of ivermectin, a Nobel Prize winning, established, safe, off-patent drug for the treatment for COVID-19, long-covid and now to assist with debilitating injuries following COVID-19 vaccines.

A letter to Dr Andrew Hill
On March 4, 2022 a mini documentary was released documenting Dr Lawrie’s interactions with Dr Andrew Hill, a key player in the global “degeneration” of ivermectin, in it’s use to save lives. – WATCH, Substack – READ

Dr Lawrie’s interviews and links in reverse chronological order

2024

June 7, 2024 – Club Grubbery: Interview w/ Dr Tess Lawrie – WATCH

May 31, 2024 – National Citizens Inquiry Canada | Regina, Saskatchewan : Dr. Tess Lawrie – WATCH

March 15, 2024 – Dr Trozzi Substack: Tess Lawrie “The Conscience of Medicine” – WATCH

February 23, 2024 – Ask Dr Drew: Ex WHO Consultant Says WHO Leadership is “Compromised” & Seizing Power Through New Pandemic Treaty w/ Dr. Tess Lawrie – WATCH

2023

December 14, 2023 – The Highwire Ep 350: HEROES OF SCIENCE – FULL, Tess Lawrie Exposes the WHO – WATCH

  • Discussion: the global health regulatory agencies’ motives are no longer about solving health crises and the powerful influence they have on governments worldwide

November 13, 2023 – Daystar Television Network “Stand Up For Truth And Justice, They Can’t Crucify All Of Us” – Dr. Peter McCullough & Dr. Tess Lawrie – WATCH, [I dare you to read without a tear (emoji heart for Tess)] – READ

  • “I’m sure you can imagine my disappointment when I did not get to fulfil my mission to share Jesus’ succinct message for Humanity.”…”Let’s not be afraid by what is happening but, equally, let’s not sit back with complacence either. Let’s love one another and stand up for Truth and Justice.”

October 28, 2023 – Dr Tess Lawrie Substack: My Letter to Dr Andrew Hill Video – READ

August 20, 2023 – Dr Tess Lawrie Substack: Dr Andrew Wakefield was right all along – His research on vaccine harms was “just the beginning”. Was an “ethically challenged man” recruited to keep him quiet? – READ

March 18, 2023 – Mistakes Were NOT Made: An Anthem for Justice (by Margaret Anna Alice; Read by Dr. Tess Lawrie) – WATCH, READ

  • March 29, 2023 – WCH General Assembly #82: The Story Behind Mistakes Were NOT Made: An Anthem for Justice (by Margaret Anna Alice) – WATCH, READ
  • January 2, 2023 – Margaret Anna Alice Through the Looking Glass Substack: Mistakes Were NOT Made: An Anthem for Justice – The Poem – READ

March 16, 2023 – preprint: Strategies for the Management of Spike Protein-Related Pathology – Halma, Tess Lawrie et al – READ, Dr McCoullough – SUBSTACK

2022

December 4, 2022 – Dr Tess Lawrie: Are Covid boosters causing cancer? a talk with Professor Angus Dalgleish Professor of Oncology at St George’s University of London – READ & WATCH

September 25, 2022 – Tess Talks with Rick Heimens: Aviation safety: a chopper pilot’s perspective (from Netherlands) – WATCH & READ

  • “vaccinated pilots are no longer compliant with aviation safety regulations. Aviation authorities are breaking their own rules and putting both flight crew and passengers at risk”

September 4, 2022 – Radical w/Maajid Nawaz #20 – On What Else Could They Have Lied To You About? and interview with Dr Tess Lawrie – WATCH, GETTR

August 20, 2022 – CHD: 75th Annual Commemoration of the Nuremberg Code – Tess Lawrie – WATCH

August 11, 2022 – Neil Oliver Wakes Up With Dr Tess Lawrie – Full Episode #1 – When the Covid 19 storm broke Dr Tess Lawrie immediately knew something was wrong – in the first episode of his new series Neil hears her story, the scientist who questioned Covid. – WATCH, SUBSTACK, EXCERPT, Neil Olivers CHANNEL

August 8, 2022 – A Better Way | Health Conference Ireland: Presentations of evidence-based insights relating to Covid-19 and the health effects of the Covid-19 injection products – Dr Tess Lawrie – WATCH

July 17, 2022 – GB News: Health Canada approves Covid jabs for children under five: Neil Oliver Live guests react with Tess Lawrie – WATCH

July 9, 2022 – CHD | ‘Friday Roundtable’ Episode 15: FDA — FIXED by Pharma – WATCH

June 30, 2022 – Maria Zeee: Dr. Tess Lawrie – Worldwide Coalition, Monkeypox, Global Fertility Problems from Injections and Saying ‘No’- WATCH

June 28, 2022 – The New American: Dr. Tess Lawrie: RECALL The Covid Shots – WATCH

June 27, 2022 – The BiRD Group Dr. Tess Lawrie talks with Dr. Dolores Cahill about why the legal system is not lawful – WATCH, BACKUP

June 4, 2022 – Corona Investigative Committee – Session 107: Cancel Unculture – Dr Tess Lawrie – WATCH, FULL @12min

Ivermectin Pushback: Why Would Merck, the Original Patent Holder, Come Out With Safety Concerns? – EXCERPT

So Merck, which has competing drugs to treat COVID and prevent COVID, came out with a statement saying that there’s a concerning lack of safety data. Now, in actual fact, Merck had done the original safety studies, and in 2002, they showed that ivermectin was safe even at 10 times the usual dose, so this was very concerning and clearly a conflicted statement that then began to be used by these health authorities.”

Tess Lawrie
  • As Safe as Other Vaccines? Really? There’s No Way the WHO Could Know This in Such Short Time – EXCERPT
  • WHO Ivermectin Contradictions: “There’s Something Really Odd Going On Here” – EXCERPT
  • The World Health Organization came out with a therapeutics and COVID-19 guideline document, where they said that the evidence for ivermectin was of very low certainty and that it should not be recommended outside of a clinical trial.
  • But the data doesn’t match the message. Their data showed an 81% reduction in deaths, and yet they said that the evidence was uncertain
  • Memory-Holed: The WHO Document from 2015 That Can No Longer Be Found. – EXCERPT
  • Archive of the WHO 2015 document – “Developing global norms for sharing data and results during public health emergencies. Statement arising from a WHO Consultation held on 1-2 September 2015” – HERE, MEETING
  • For ivermectin, only negative studies were published, with hindrance of study publication and discrediting of scientists who reported positive results.

According to that document, ivermectin should be authorized, at the very least given emergency use authorization like the new drugs that are being offered, but the page has now been taken down.”

Tess Lawrie

May 24, 2022 – WCH: ‘Historic’ Better Way Conference Hailed as Birthplace of New Integrative Health Movement  – READ

  • “Ambitious in its agenda and delivery, the conference acted as a springboard for the creation of a new vision; mapping out the future of integrative healthcare and wellbeing rooted in sovereignty, informed consent, and personal empowerment.”…

May 20, 2022A Better Way Conference Bath, UK: Organised by Tess Lawrie and the World Council for Health – All Conference Presentations – HERE, A Better Way CHARTER, Announcement – ARCHIVE
Conference press release – HERE, Cancelled venue! – READ

Opening Ceremony with Del Bigtree and Dr. Tess Lawrie – WATCH, BACKUP
Dr. Tess Lawrie: One Solution to Big Pharma’s Monopoly | Better Way Conference – WATCH

April 13, 2022 – Dr Lawrie “Urgent – my video call with the WHO this morning – We can’t let them get away with their power grab attempt” – WATCH, SUBSTACK, MESSAGE

April 18, 2022 – Zeee Media: Dr. Tess Lawrie – The World is At Risk – The WHO Pandemic Treaty – WATCH, EXCERPT
Dr. Lawrie Details Why the WHO Treaty is a Direct Threat to Humanity – EXCERPT2

March 29, 2022 – Dan Hanson of Health Alliance Australia speak with world-renowned research expert, Dr Tess Lawrie on Ivermectin – WATCH, READ

March 23, 2022 – Australia’s COVID UNDER QUESTION a cross-party inquiry into the Government’s response to COVID hosted by Senator Malcolm Roberts – Dr Tess Lawrie – WATCH, CHANNEL

March 10, 2022 – James Wells interviews Dr Tess Lawrie – Dr Tess Lawrie has been on a rollercoaster journey trying to raise awareness of evidence on early treatments for covid. Along the way Tess encountered censorship, corruption and misinformation – WATCH

March 4, 2022 – Oracle Films mini-documentary: “A Letter to Andrew Hill” – WATCH, Oracle

A letter to Dr Andrew Hill
Mini-documentary telling Dr Lawrie story regarding ivermectin systematic review – WATCH

March 3, 2022 – The Highwire: Del sits down for a one-on-one with the former W.H.O. consultant & research scientist, Tess Lawrie MD, PhD – WATCH

January 23, 2022 – KLIM.news: Dr. Tess Lawrie is demanding an investigation and immediate stop to the experimental “vaccines.” – WATCH

January 23, 2022 – World Council for Health: Dr. Tess Lawrie: The Opportunity for Real Change Has Arrived – #DefeatTheMandates #TheresABetterWay with Dr Tess Lawrie – WATCH

January 22, 2022 – Defeat the Mandates rally – Speech via Zoom by Tess Lawrie – WATCH

2021

December 27, 2021 – Maria Zeee with Tess Lawrie – Omicron is a Distraction – WATCH

December 17, 2021 – Daniel Horowitz: Story of 2021: The War on Treatment That Killed Millions | Guest: Dr. Tess Lawrie – PODCAST

November 26, 2021 – Discussion with Australian Politicians – Dr Tess Lawrie et alWATCH

November 4, 2021 – Maria Zeee with Dr Tess Lawrie – These Vaccines are Not Safe. PART 1, PART 2

September 14, 2021 -International COVID Summit – Sharing evidence on ivermectin in the covid health emergency – WATCH

August 16, 2021 – Oracle Films: Interview with Dr Tess Lawrie – she speaks about ivermectin’s effectiveness, a long-time safe medicine, to treat and prevent COVID-19 and how health authorities are systematically ignoring the evidence – WATCH, BACKUP, YouTube

July 24, 2021 – World Ivermectin Day invite by Dr Lawrie – WATCH, OFFICIAL

June 21, 2021 – American Journal of Therapeutics: Ivermectin for Prevention and Treatment of COVID-19 Infection: A Systematic Review, Meta-analysis, and Trial Sequential Analysis to Inform Clinical Guideline – READ, PubMed

July 17, 2021 – DarkHorse Podcast with Tess Lawrie & Bret Weinstein – WATCH

July 15, 2021 – Mark Dolan TalkRadio UK speaks with Dr Lawrie – Yellowcard, ivermectin, lockdowns and vaccines – WATCH, Original, Telegram

April 26, 2021 – Dr Been Medical Lectures: Your Questions Answered By Dr. Tess Lawrie – WATCH, ARCHIVE

April 24-25, 2021 – 1st International Ivermectin for COVID-19 Conference with Dr Lawrie – WATCH, OFFICIAL, EVENT, SPEECH, Those Who Control the Trials Control the Outcome: Dr. Tess Lawrie’s Impassioned Plea Against the Politicization of Medicine – EXCERPT

March 15, 2021 – Trial Site News: Dr. Tess Lawrie Discusses her Ivermectin Meta-Analysis, the FDA, and Dr. Andrew Hill – WATCH, ARCHIVE

February 20 – 2021 – The BIRD 2: Zoom meeting to review the evidence on IVM to potentially prevent and treat COVID-19, where to now – WATCH

January 25, 2021 – Hibberd Health – Dr. Tess Lawrie discusses her COVID-19 ivermectin meta-analysis – WATCH

January 3, 2021 – ReserchGate: URGENT COVID-19 information: Ivermectin reduces the risk of death from COVID-19 – a rapid review and meta-analysis in support of the recommendation of the Front Line COVID-19 Critical Care Alliance. – READ

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Dr Geert Vanden Bossche https://totalityofevidence.com/dr-geert-vanden-bossche/ Tue, 01 Mar 2022 22:59:38 +0000 https://totalityofevidence.com/?p=2433 Dr Geert Vanden Bossche is a Doctor of Veterinary Medicine who has specialist expertise in virology and vaccinology, Geert has worked in industry in the construction of vaccines, and in the non profit sector working to bring immunity to larger…

The post Dr Geert Vanden Bossche first appeared on Totality of Evidence.

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Dr Geert Vanden Bossche is a Doctor of Veterinary Medicine who has specialist expertise in virology and vaccinology, Geert has worked in industry in the construction of vaccines, and in the non profit sector working to bring immunity to larger numbers of people. For much of his career has worked for Big Pharma, Big Vaccine and has received funding from Big Gates! He has earnt the right to have an opinion.

The big message Geert has been trying to warn authorities of is that mass vaccination in the middle of a pandemic with a vaccine that is “leaky” (not fit for purpose) will inevitably put “evolutionary pressure” on the virus and thus select for variants, potentially one that is more lethal than that which you intend to control. There is no hope in achieving vaccine herd immunity with these experimental, leaky, COVID-19 vaccines, especially for a coronavirus that is rapidly mutating and produces variants that escapes vaccine immunity! STOP MASS VACCINATION!

Dr Geert Vanden Bossche

Geert’s Official Links:

  • Website HERE,
  • Bio HERE,
  • Substack HERE,
  • Website videos HERE,
  • Rumble channel HERE,
  • YouTube HERE,
  • Twitter HERE
  • Gab – HERE
  • Vejon Health w/ Dr Philip McMillan often interviews Geert – HERE
  • The Inescapable Immune Escape Pandemic – BOOK
The Inescapable Immune Escape Pandemic

Videos in reverse chronological order

This list is not complete. Check out links above for more videos and articles by Geert

2024

July 4, 2024 – Geert on Substack: Like SARS-CoV-2, I’m ready for a major change… – READ moving to Alliance for Naural Health – Health Creation Faculty – WEB

  • “In closing, Nature is now streamlining the evolutionary dynamics of the virus, shifting them from a complex and diversified pattern to a trajectory determined solely by increasing collective immune pressure on viral virulence. This means that in highly C-19 vaccinated populations, the immune escape pandemic is on the brink of transitioning from its chronic phase (long Covid) to its hyperacute phase (enhancement of severe disease) and is therefore likely to escalate excess deaths”…
  • “This is because the mass vaccination program not only resulted in profound immune dysregulation but also led to large-scale vaccine breakthrough infections caused by more infectious and recently more transmissible Omicron descendants (KP.2, KP.3, LB.1). As transmission efficiency increases, more animal reservoirs are being generated due to the transmission of SARS-CoV-2 variants from humans to animals, a phenomenon known as ‘reverse zoonosis’.”
  • “Nature is unlikely to proceed with populations consisting of large cohorts of vaccine-debilitated individuals left unprotected by their immune system and lacking affordable access to safe and effective antivirals.
  • Those who are healthy and unvaccinated will indeed not be affected.”
  • Last Call to join this forum and stay ahead of the curve on a “rapidly-evolving crisis” imminently facing mankind.”

June 17, 2024 – Voice for Science and Solidarity: The Endgame: The Outcome of Vaccine-Associated Viral Phenotype Selection Will Overrule the Effect of Vaccine-Associated Human Genome Editing – READ

  • Question Geert often gets asked: “To what extent could the integration of bacterial DNA, heavily contaminating Pfizer and Moderna vaccines, cause changes or damage to the genome of C-19 vaccinated individuals? Could such integration into germ cells potentially even lead to these changes being passed on to future generations?”
  • “As the replication cycle of SC-2 [SARS-CoV-2] takes only about 10 hours, such new phenotypes can also increase their prevalence very rapidly.”
  • “I’ve repeatedly emphasized that mRNA vaccines not only promote viral immune escape but also cause immune refocusing … This phenomenon involves the immune response increasingly targeting conserved spike-associated epitopes of the virus, often containing self-mimicking motifs.” [homology to human protein epitopes – i.e. autoimmune response]

I believe it is evident that the global impact of the large-scale C-19 vaccination program on the virus’s virulence will manifest much sooner than the detrimental impact of the DNA-contaminated mRNA vaccines on the population’s health status (including reproductive health).

Geert Vanden Bossche

May 29, 2024 – Vejon Health w. Philip McMillan: Is this Geert’s Final Warning on Covid? GEERT: Bird Flu – a Distraction from COVID? – WATCH & READ, YouTube

April 3, 2024 – Geert’s Substack: How often have I said to you that when you have eliminated the impossible, whatever remains, however improbable, must be the truth? – READthe calm before the tsunami’,

  • “This game of cat and mouse continues because highly Covid-19 (C-19) vaccinated populations cannot develop herd immunity.”
  • “What we will eventually observe is that this highly effective process of viral adaptation will ultimately confer an absolute fitness advantage to a Coronavirus (CoV) that is both structurally and functionally completely different from SARS-CoV-2 (SC-2) and its variants…..(I call it ‘HIVICRON’: a highly virulent CoV that will replace the entire Omicron family)”
  • “The unvaccinated individuals who are in good health and have not previously suffered from severe C-19 disease will not be affected by this new CoV…”
  • “As the immune escape pandemic will transition from its ‘chronic’ phase (i.e., characterized by a high prevalence of ‘Long COVID’!) to its final…Given the insidious nature of the current evolution, I am referring to the current period as ‘the calm before the tsunami’ and warning that ‘societies in highly C-19 vaccinated countries will be caught off guard’.”

“I seriously doubt the stakeholders of this mass vaccination program were clever enough to realize that their ‘shit’ experiment would quickly emerge as the most spectacular gain-of-function experiment ever conducted in the history of biology (one that was directly conducted on our very own human species!!!)…The fact remains that soon it will become evident how, due to their [public health et al] actions, a fairly harmless virus was transformed into a bioweapon of mass destruction.”

Geert Vanden Bossche

March 31, 2024 – KunstlerCast 398 – Dr Geert Vanden Bossche and the Coming Acute Crisis of Covid among the Vaccinated – LISTEN, Gateway Pundit – CREDIT

January 15, 2024 – IPAK-EDU Director’s Science Webinar: Geert Vanden Bossche: “What happens if a pandemic involving a virus naturally causing acute self-limiting infection fails to generate herd immunity?” – WATCH

January 13, 2024 – Vejon Health w/ Dr Philip McMillan: Potential Clinical Implications of Geert’s Viral Shift Predictions –WATCH

  • Recent further unusual patterns in viral evolution have indicated to him that the virus is now making more changes which will allow it to evade all vaccines

2023

December 14, 2023 – Vaccine Safety Research Foundation (VSRF) Live #106: Dr. Geert Vanden Bossche on “White Lung” Pneumonia – WATCH

September 21, 2023 – Geert Vanden Bossche Substack: How many more times will I have to tell you that this ‘immune escape’ pandemic will not have a happy ending? – READ

  • “The exotic and highly infectious nature of the currently circulating variants raises questions. New emerging variants are now succeeding each other at a rapid pace (e.g., FL.1.5.1, BA.2.86, EG.5). While they share a phylogenetic relationship, they have become so antigenically distinct from their predecessors that they should no longer be considered mere variants but rather different serotypes.”
  • “…viral evolutionary dynamics are no longer driven by ‘herd’ immune selection pressure on viral infectivity.”

August 17, 2023 – The Highwire Ep 333: INESCAPABLE – FULL, Is a Deadlier Pandemic on the Horizon? A discussion with Geert Vanden Bossche – WATCH

June 9, 2023 – Vejon Health w/ Dr Philip McMillan: Vaccine Immune Confusion with Geert Vanden Bossche and Dr Rennebohm – WATCH

March 13, 2023 – Geert Vanden Bossche: Expert Immunologist Raises Concerns About the Devastating Effects of Mass Vaccination – WATCH, READ

February 19, 2023 – Book released: The Inescapable Immune Escape Pandemic: Nobody can conceal the science that nature is now desparate to unveeil. Society in highly vaccinated countries will be caught by surprise – TWEET, TWEET, READ, Amazon has pulled both paper book as well as e-book from its webshop – TWEET

January 30, 2023 – Geert Vanden Bossche and Paul Alexander: Stop COVID vaccines, elderly could be killed, do not give to children – WATCH, READ

January 22, 2023 – Pandemic Strategies: Lessons and Consequences – Conference in Stockholm, Sweden: Omicron has not been a blessing but a scourge – Dr Geert Vanden Bossche – “How to turn a viral pandemic into an inescapable immune escape pandemic? – WATCH, The Conference – MORE

2022

November 26, 2022 [?] – Vaccine Safety Research Foundation: VSRF Thanksgiving Marathon [FLASHBACK] – Reel 4: Geert Vanden Bossche, Alex Berenson, & Pierre Kory (interview with Steve Kirsch) – WATCH

November 12, 2022 – Bright Light News: Covid Vaccines Driving Dangerous Variants & Immune Suppression – WATCH, READ Immunity of the Vaxxed Fundamentally Different From the Unvaxxed – EXCERPT, READ

November 6, 2022 – Good Morning CHD: ‘Good Morning CHD’ hosted by Syed Haiden: Are Vaccines Driving Virus Mutation? with Geert Vanden Bossche – WATCH, WATCH, READ

October 8, 2022 – Voice for Science and Solidarity: It is 5 past 12 – Geert’s last video broadcast – WATCH, TRANSCRIPT

“I can no longer stand it. For me, it has become unbearable to see how our health authorities, our experts and governments are still trying to make people believe that the COVID-19 vaccines are safe and that they will be able to control the pandemic”

Geert Vanden Bossche

October 7, 2022 – Freeman Interviews with James F Wells: Freeman interviews Geert Vanden Bossche – WATCH

“Decision makers, in WHO, will be held responsible, accountable and liable for the dramatic consequence that this biological experiment on human beings could possibly entail”

Geert Vanden Bossche

August 27, 2022 – CHD | ‘Friday Roundtable’ Episode 22: With Geert Vanden Bossche, DVM, Ph.D. – WATCH

August 17, 2022 – The New American Magazine: Dr. Geert Vanden Bossche: Warning Against Monkeypox Vaccinations – WATCH, READ

August 5, 2022 – Voice for Science and Solidarity: Vaccination of vulnerable groups against monkeypox virus (MPV) in a highly C-19 vaccinated population will drive adaptive evolution of MPV and ignite multi-country epidemics in poorly C-19 vaccinated countries – Monkeypox by Geert Vanden Bossche – READ

July 14, 2022 – The New American: Dr. Geert Vanden Bossche: Covid Mass Vaccination Triggering New Pandemics and Epidemics – WATCH, READ

  • The current monkeypox outbreak is a result of the Covid vaccinations that are connected to Covid reinfections and the related reactivation of cytotoxic t-cells, claims Dr. Vanden Bossche

July 7, 2022 – The Highwire Episode 275: (The Better Way Conference) THE FORBIDDEN DEBATE “jabs” (Del, Geert, Robert et al) – WATCH

July 6, 2022 – Don’t vaccinate your children with covid-vaccines – Dr. Geert Vanden Bossche – WATCH, ARTICLE

June 17, 2022 – Bret Weinstein: A Tale of COVID Trade-Offs: Vaccines vs Innate and Natural Immunity with Dr. Geert Vanden Bossche – WATCH, BACKUP

  • “Geert Vanden Bossche stated in the interview with Bret Weinstein that the Spike Protein would be the right choice as a viral target due to its role in accessing cells…However, considering mutations, especially in Coronaviruses, vaccination with the Spike Protein as viral target can’t work. That’s the reason why we have not seen any vaccines for coronaviruses before SARS-CoV-2. It is not possible to catch up with the mutations of the Spike Proteins” see excerpt for more.
  • Why haven’t we seen any vaccines against coronaviruses before SARS-COV-2 came along? – EXCERPT

RNA viruses are known for their remarkably high error rates and, thus, the rapid generation of mutations. Despite possessing some proof-reading capacity (a relatively rare function for an RNA virus), SARS-CoV-2 has been accumulating roughly 24-25 substitutions per year

Geert Vanden Bossche
Source: coronavirus has many proteins vs mRNA vaccine targets just the spike protein
Source: Coronavirus “spike” protein has the highest rate of mutations, yet this is the protein the vaccine manufactures targeted!

June 10, 2022 – The New American – Dr. Geert Vanden Bossche: Covid Infection, Disease to Aggravate in Vaccinated – WATCH

Because we were [only] supressing the infectiousness of the virus, but we could not prevent the virus from replicating and transmitting. That the virus has got an opportunity to overcome the immune pressure of the viral infectiousness that we were putting through the mass vaccination, and the result has been more infectious variants.“…“as long as the virus is capable of replicating and transmitting …the virus is evolving towards a situation where it will overcome the pressure of the viral virulance…

Geert Vanden Bossche

“…in other words the unvaccinated will be more and more spontaneously protected against the disease and even against infection.

  • The mass vaccination campaign against Covid has been a “blunder of unprecedented scale” that would likely result in “a global catastrophe without equal,” warned world-class Belgian scientist Dr. Geert Vanden Bossche at the beginning of the vaccines’ rollout.

June 9, 2022 – Why You Never Mass Vaccinate into a Pandemic, Monkeypox & a Better Way -Geert Vanden Bossche – WATCH

June 3, 2022 – Dr. Geert Vanden Bossche and Dr. Paul Elias Alexander discuss the damage by the COVID vaccines in subverting the innate immune system in children – WATCH

May 18, 2022 – Zeee Media: Dr. Geert Vanden Bossche – ADE, Evolution of the Virus & Expected Excess Deaths – WATCH

May 17, 2022 – Then [They] Came for the Canadians – A digital conference of world-renowned experts presenting Candanians with the latest Covid science and resources, and calling for an end to totalitarian government interventions (5 hrs) – FULL, TRAILER, Parts 1-4 – HERE, Geert Vanden Bossche – EXCERPT

May 5, 2022 – The Highwire Episode 266: Acclaimed vaccinologist, Geert Vanden Bossche, sits down for his second groundbreaking interview with Del Bigtree to explain why the intense pressure mass vaccination is putting on the COVID-19 virus will likely drive it to become catastrophically deadly – WATCH, FULL,
The deaths will be unprecedented – EXCERPT

April 8, 2022 – Dana Loesch – DEADLIER VARIANTS? Dr. Geert Vanden Bossche On What To Expect In The Near Future And Why – WATCH

February 23, 2022 – Dan Hanson of Health Alliance Australia speaks with world renowned Virologist and Vaccinologist, Dr Geert Vanden Bossche – WATCH, READ

February 23, 2022 – The Defender Podcast: Interview with Robert F Kennedy Jr – LISTEN

February 21, 2022 -Empire Diaries: Vaccinologist – “Not surprised that vaccinated are dying” – WATCH

February 12, 2022 – TrialSite News – Geert Interview Series | PART 7: What is immunity? – WATCH

February 11, 2022 – TrialSite News – Geert Interview Series | PART 6: What Is A Virus Anyway? – WATCH

February 9, 2022 – TrialSite News – Geert Interview Series | PART 5: What is the best thing to ask your doctor? – WATCH

February 8, 2022 – TrialSite News – Geert Interview Series | PART 4: How a layperson can sift through contradictory information – WATCH

February 1, 2022 – TrialSite News – Geert Interview Series | PART 3: Who is Geert Vanden Bossche? – WATCH

January 31, 2022 – TrialSite News – Geert Interview Series | PART 2: Geert’s Views On The Booster Shot – WATCH

January 28, 2022 – TrialSite News – Geert Interview Series | PART 1: Should we vaccinate children? – WATCH

2021

December 23, 2021 – COVID19 experts meet with Australian Politicians – Geert Vanden Bossche – WATCH

November 30, 2021 – The Highwire – Continued mass vaccination will only push the evolutionary capacity of SARS-CoV-2 Spike protein beyond the Omicron version by Geert – READ

November 18, 2021 – The Highwire Ep 242: The Vanden Bossche Interview – WATCH, FULL, BACKUP

October 1, 2021 – The Highwire: ANDEN BOSSCHE & MALONE: COVID-19 GIANTS UNITE – WATCH

September 25, 2021 – Critical Views on Immunology and Vaccines: Meeting of the Giants: Vanden Bossche and Malone – WATCH, The Highwire – COVERAGE & HERE

September 2021? – Urgent call to WHO to “urgently open scientific debate on how human interventions in the COVID-19 pandemic are currently driving viral immune escape” – WATCH

August 3, 2021 – The Highwire Ep 226: Looking back and featuring Geert’s warning to the world – WATCH

June 2, 2021 – Geert’s Message: The insidious face of a pandemic of variants – WATCH

Comment from under Geert’s message – HERE

April 22, 2021 – DarkHorse Podcast with Geert Vanden Bossche & Bret Weinstein – WATCH, TIMESTAMPS

April 22, 2021 – Geert’s Message: Why do we always need to learn things the hard way? Summary, key lessons and conclusions – WATCH

April 21, 2021 – Geert’s Message: Asymptomatic infection fuels spread of more infectious SARS-CoV-2 variants – WATCH

April 14, 2021 – Geert’s Message: How different dynamics of Covid19 pandemic in different parts of the world lead to the same outcome – WATCH

April 8, 2021 – Geert’s Message: Current evolution of the Covid-19 pandemic requires a more rational approach to human intervention – WATCH

March 15, 2021 – Covexit News: A discussion with Vanden Bossche and McCullough – WATCH

March 11, 2021 – Geert Vanden Bossche’s Open Letter to the WHO: Urgent call to WHO: time to switch gears – WATCH

March 11, 2021 – Why should current Covid-19 vaccines not be used for mass vaccination during a pandemic? – WATCH

March 6, 2021 – McMillan Research: Mass Vaccination in a Pandemic – Benefits versus Risks with Geert Vanden Bossche – WATCH, RUMBLE, BACKUP, BACKUP

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John O’Looney https://totalityofevidence.com/john-olooney/ Sun, 27 Feb 2022 11:41:34 +0000 https://totalityofevidence.com/?p=2321 John O’Looney has been a funeral director for 15 years and has his own business Milton Keynes Family Funeral Services in the UK. John shares his alarming pandemic experience starting in late November 2019 when he saw a “blow-up pandemic…

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John O’Looney has been a funeral director for 15 years and has his own business Milton Keynes Family Funeral Services in the UK. John shares his alarming pandemic experience starting in late November 2019 when he saw a “blow-up pandemic mortuary” in a local hospital which was set up in preparation for “something really horrible coming!”

John OLooney - Funeral Director

In 2021, as the vaccines rolled out he has been witness to a spike in unusual deaths which he says other funeral directors have also witnessed but are too scared to speak out.

MUST WATCH: John first spoke out in September 2021 – WATCH

  • Milton Keynes Family Funeral Services – WEBSITE

Interviews in reverse chronological order

2024

March 15, 2024 – Cafe Locked Out: John O’Looney & Richard Hirschman, Finally Two Great Funeral Directors Together – WATCH, READ

2023

August 20, 2023 – Brucha Weisberger (organiser): Rofim International Mega Event: Have You Stopped Trusting Yet? – WATCH, John O’Looney – EXCERPT, Mike Yeadon – EXCERPT, Sasha Latypova – EXCERPT, READ, Meryl Nass – EXCERPT, READ

January 31, 2023 – Catherine Edwards interviews UK Funeral Director John O’Looney – Its Not too Late – WATCH

February 1, 2023 – Planet Waves FM | Eric F Coppolino: Interview with Funeral director John O’Looney – WATCH

  • “He discusses no excess deaths in 2020. Deaths from remdesivir. Mass deaths started in 2021 as soon as needles went into arms. Deaths / euthanasia of elderly people via midazolam….” – SUBSTACK

2022

December 2022 [?] – John O’Looney: Black Watch Troops Have Told Me This Is The Plan!! – United Nations soldieres, forced to sign the secrets agreement before they come in with the “immigrants” – WATCH

December 24, 2022 – Off-Grid Irealand with John OLooney – LISTEN, SPOTIFY

November 8, 2022 – John O’Looney recording: Social Care Services bringing elderly into pharmacies to get the flu jab knowing that “they’re killing them” – WATCH

October 18, 2022 – CHD ‘Good Morning CHD’ Episode 156: This Is Genocide With John O’Looney – WATCH, ‘Massive Increase’ in Death Rate Exclusively in Young Jab Recipients – EXCERPT

October 16, 2022 – CHT” ‘Good Morning CHD’ Episode 156: This Is Genocide With John O’Looney – WATCH

August 26, 2022 – Laura-Lynn Tyler Thompson: Embalmers have NEVER seen this before in the arteries of people who have “died suddenly”… with John O’Looney – TWEET, WATCH

August 12, 2022 – Global Research: Justice Won’t Come From Our “Legal” System. It Will Come From “The Collective Masses”. – READ

July 25, 2022 – Laura-Lynn Tyler Thompson:: Live With UK Funeral Director John O’Looney – WATCH

July 16, 2022 – Professor Dolores Cahill chats with John O’Looney Funeral Director (UK) on vaccine baby deaths – WATCH

July 14, 2022 – Maria Zeee – John O’Looney – Hospitals Are Covering Up Baby Deaths By Cremating Babies Themselves – SOURCE, WATCH, ARTICLE

In this interview John shares information about hospitals dealing directly with crematoria and bypassing funeral directors when dealing with dead babies! – Miscarriage rates are up! He mentions Australian doctor Luke McLindon.


March 19, 2022 – Refuge of Sinners interview with John – WATCH, EXCERPT

March 8, 2022 – Voice Of Wales with John O’Looney – @26:40 WATCH

February 14, 2022 – Grand Jury testimony by John O’Looney – WATCH, BACKUP

January 29, 2022 – Maria Zeee interviews John O-Looney: Most Deaths are Vaccine Deaths – WATCH

January 28, 2022 – Funeral Director in UK Reveals Increasing Number of Death in Vaccinated Young Adults – WATCH

2021

December 6, 2021 – Funeral Director Confirming unnaturally high number of post COVID jab deaths – WATCH

December 4, 2021 – Funeral Director Whistleblows On COVID-19 Vaccine Deaths – WATCH

November 14, 2021 – The UK Column | Brian Gerrish in discussion John O’Looney Independent Undertaker about Covid Deaths – WATCH

October 14, 2021 – RAIR Foundation: BOMBSHELL: British Funeral Director John O’Looney: Deaths Skyrocketed ‘300%’ After Covid Vaccine (Video) – READ, WATCH

I’ve never seen a death rate like it in 15 years.”

John O’Looney

October 9, 2021 – Interview with GB Resistance – WATCH

October 6, 2021 – The Corona Investigative Committee Session 72 with John O’Looney – WATCH, FULL, BACKUP

September 23, 2021 – Stew Peters Show – “Mass Vaccine Deaths and Genocide Planned” –WATCH, REPEAT

September 16, 2021 – The Crowhouse interview with John O’Looney that went viral- WATCH, BACKUP, BACKUP2

September 6, 2021 – Lindie Naughton interviews John: Death rate has spiked since the roll out of the vaccine – WATCH, BACKUP

July 16, 2021 – Dan Astin-Gregory Pandemic Podcast: THE AWAKE UNDERTAKER: WHO IS COVID-19 REALLY KILLING? – WATCH, FB, PODCAST, CREDIT

July 5, 2021 – Richie Allen show: ⁣Funeral Director warns about falsified covid death numbers – LISTEN, CREDIT

The post John O’Looney first appeared on Totality of Evidence.

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Professor Nikolai Petrosvky https://totalityofevidence.com/professor-nikolai-petrosvky/ Tue, 08 Feb 2022 10:19:00 +0000 https://totalityofevidence.com/?p=1810 Below you will find a growing collection of interviews with Professor Nikolai Petrovsky, a research scientist, medical doctor, and vaccine developer from Flinders University in South Australia, who in 2021 was granted registration in Iran for his COVID-19 protein-based vaccine…

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Below you will find a growing collection of interviews with Professor Nikolai Petrovsky, a research scientist, medical doctor, and vaccine developer from Flinders University in South Australia, who in 2021 was granted registration in Iran for his COVID-19 protein-based vaccine called COVAX-19.

Professor Nikolai Petrovsky is the Director of Endocrinology (Flinders Medical Centre), Professor of Medicine (Flinders University), Vice President of the International Immunomics Society, Founder and Research Director at Vaxine and the developer of COVAX-19 and Spikogen.

  • Flinders Univesity people – ARCHIVE
Professor Nikolai Petrovsky

Professor Petrovsky will be the expert witness in the upcoming South Australian Judicial Review, to give expert testimony on behalf of the Applicants, challenging the legality of the grounds for vaccine mandate Directions, issued by the Police Commissioner under the State of Emergency.

Prof Petrovsky video interviews in reverse chronological order

2024

April 18, 2024 – Club Grubbery: Breaking: Professor Nik Petrovsky appears with his legal counsel Jay Vidanage after Federal Court refuses to prevent the closure of his research facility by direction of SA Health and Flinders University – WATCH, TWEET

  • Judge orders Prof Petrovsky to exit his huge research facility in 24 hours. With current and ongoing research that is saving peoples lives, will have to just stop, and his patients will die.
  • He has been targeted by the government becasue of his being an expert witness against their narrative.

2023

December 14, 2023 – Club Grubbery: Graham and John speak with Nik Petrovsky and Senator Malcolm Roberts… – WATCH

June 15, 2023 – The Chris Smith Show | TNT Radio: The Hon. Mark Latham MLC & Dr Nikolai Petrovsky on The Chris Smith Show – @28min LISTEN

“…we ourselves [Vaxine] explored an mRNA vaccine early on in this…we were intrigued on the science side, we never thought this as a serious alternative, because, as you say, there was no data whatsoever, its a very new technology no matter what anyone says, we really didn’t have the human experience with the technology that you would need.

Normally…it’s all about building up a safety portfolio for a new vaccine technology and that takes about 20 years to build.”

“We never seriously thought mRNA was going to be anything other than a science project”

It’s never been a more dangerous time to speak the truth than during the last 3 years.

Prof. Petrovsky [@34:50]

April 17, 2023 – BASED with Senator Alex Antic Ep #1: Nikolai Petrovsky – Australia’s Pandemic Response – WATCH

May 9, 2023 – Ask Dr. Drew: Furin Cleavage Site Is KEY To Covid’s Origin: Nikolai Petrovsky w/ Dr. Kelly Victory – WATCH, READ

2022

June 29, 2022 – Australian Medical Professionals’ Society (AMPS) Medico Legal Summit 2022 with Prof Nikolai Petrovsky – WATCH

July 26, 2022 – Petrovsky comments on FDA’s October 2021 COVID-19 vaccine formulation change – without any clinical trials – ARTICLE

“I’ve been doing vaccine development for a long time and normally regulators say the minute you change something in a formulation that may change its behaviour in a material way, you have to go back to square one and establish safety all over again, to show the change mightn’t have adverse consequences. The FDA apparently did not do this in this case,

Why is no one questioning this? It’s the regulator’s job to act on the side of caution and assume any change could have harmful effects until proven otherwise.” 

…“No-one is questioning the safety of the buffer – it’s about how it might change the properties of this particular mRNA vaccine in its lipid nanoparticles,”

“Biologics have a trillion times more complexity than small molecule drugs, biologics can exhibit completely different properties depending on how the protein, or in this case, mRNA chain folds up. That’s why you need different FDA departments to regulate them, because the things that go wrong with biologics are much more complex than the things that go wrong with small molecule drugs,”

Professor Petrovsky

February 15, 2022 – Article referencing Covax-19 – COVID-19 vaccines: Is the spike protein “toxic” ? – READ

2021

December 20, 2021 – Maria Zeee : TGA has granted provisional determination for COVAX-19 – WATCH

December 20, 2021 – TGA grants provisional determination to Vaxine Pty Ltd for its COVID-19 recombinant protein vaccine – in relation to their COVID-19 vaccine, Recombinant CoV-2-S-ΔTM protein with Advax-CpG55.2 adjuvant – READ, ARCHIVE

  • “This recombinant (genetically engineered) protein vaccine will be considered for active immunisation to prevent COVID-19 caused by SARS-CoV-2. “
  • “The granting of a provisional determination means that the TGA has made a decision that Vaxine Pty Ltd is now eligible to apply for provisional registration for the vaccine in the Australian Register of Therapeutic Goods (ARTG).?

December 8, 2021 – ABC News: COVID-19 vaccine mandate loophole of signing up for COVAX-19 trial closed by SA government – South Australian authorities will no longer allow those participating in a vaccine trial to be exempt from state government vaccine mandates. READ

  • “Adelaide-based researcher Nikolai Petrovsky’s bid for his locally-developed COVID-19 vaccine, COVAX-19, to be approved for use in Australia has raised more than $750,000.”
  • But in a new direction issued today, SA Police said “taking part in a COVID-19 vaccination trial is no longer a valid reason to be exempt”.
  • [TGA putting up road blocks for “traditional” like vaccine, promoting new technology vaccine platforms like mRNA!]

December 8, 2021 – JP Drake (#31) 3hr in depth interview on vaccines and Big Pharma with Nikolai Petrovsky – WATCH, LISTEN

November 8, 2021 – Zeee Media: Professor Nikolai Petrovsky – The current MRNA COVID-19 vaccines are not safe or effective – WATCH

November 19, 2021 – Trial Site News – Dr Petrovsky speaks about Australian situation – WATCH

November 16, 2021 – Trial Site News – Dr Nikolai Petrovsky Discusses His Novel Vaccine for COVID-19 – WATCH

November 5, 2021 – AFIPN report Tim Jaeger: in-depth interview with Prof Petrovsky – WATCH, Original PART 1, PART 2

October 28, 2021 – Public Forum with Prof Petrovsky – WATCH, FB

October 22, 2021 – Vaccine Adverse Events, Mandates and Secrecy in Australia with Discernable – WATCH

September 24, 2021 – Vaccine: Immunisation of ferrets and mice with recombinant SARS-CoV-2 spike protein formulated with Advax-SM adjuvant protects against COVID-19 infection – Li, Petrovsky et al – READ

  • Four researchers on the paper, including Professor N Petrovsky, are affiliated with Vaxine Pty Ltd which holds the rights to COVAX-19™ vaccine and Advax™ adjuvants.
  • Part NIAID funding grant number HHS-N272201400053C

August 24, 2021 – SciMex press release: EXPERT REACTION: Modelling predicts 80 per cent adult COVID-19 vaccination won’t be enough – READ

  • “The results of this modelling vary from work by the Doherty Institute that the government’s vaccination targets are based on.”
  • “We need to be extremely cautious about making policy decisions based on just a single model. Such models are extremely sensitive to their inputs and assumptions, and can easily provide misleading results…” Petrovsky
  • “The Doherty model is based on assumptions that the two current vaccines provide high levels of sustained protection against delta virus transmission, assumptions poorly supported by available data….”
  • August 3, 2021 – EXPERT REACTION: Doherty Institute modelling shows way out of lockdowns incl Prof Booy- READ
    • Re their statement “Modelling from the Doherty Institute used to set the federal government’s vaccination targets for reducing COVID-19 restrictions has been released. The modelling shows vaccination rates of 70 and 80 per cent can significantly reduce transmission, and there is a necessity to vaccinate ‘key transmitting age groups’ as a priority.”
    • Doherty Modelling Report for National Cabinet 30 July 2021 – PDF

August 12, 2021 – SciMex press release: COVID-19 vaccine trials progress after safety study – READ

  • “A South Australian-developed SARS-CoV-19 vaccine is preparing to progress to final stages of human clinical trials after early animal testing confirmed its safety and effectiveness in preventing COVID-19 lung infection.”
  • September 24, 2021 – Vaccine: Immunisation of ferrets and mice with recombinant SARS-CoV-2 spike protein formulated with Advax-SM adjuvant protects against COVID-19 infection – Li, Petrovsky et al – READ

June 24, 2021 – SciMex press release: EXPERT REACTION: Origin of COVID-19 remains a mystery – READ

  • Scientists using computer modelling to study SARS-CoV-2… have discovered the virus is most ideally adapted to infect human cells – rather than bat or pangolin cells, again raising questions of its origin.”
  • “The scientists, from Flinders University and La Trobe University, used genomic data from the 12 animal species to painstakingly build computer models of the key ACE2 protein receptors for each species. These models were then used to calculate the strength of binding of the SARS-CoV-2 spike protein to each species’ ACE2 receptor.
  • Surprisingly, the results showed that SARS-CoV-2 bound to ACE2 on human cells more tightly than any of the tested animal species, including bats and pangolins. If one of the animal species tested was the origin, it would normally be expected to show the highest binding to the virus.”

June 24, 2021 – Nature: In silico comparison of SARS-CoV-2 spike protein-ACE2 binding affinities across species and implications for virus origin– Piplani, Nikolai Petrovsky et al – READ, Rand Paul – CREDIT,

  • “Spike protein exhibited the highest binding to human (h)ACE2 of all the species tested…These findings show that the earliest known SARS-CoV-2 isolates were surprisingly well adapted to bind strongly to human ACE2…”
    • [This is unsusal for a virus to be so well adapted so early, its as though it was developed in a lab and perfected by running it through humanises mice]
  • Jan 5, 2022 – Vision Times: Scientists Using Oracle Supercomputing Find SARS-CoV-2 Is ‘Highly Adapted’ for Humans – READ, National Pulse: Virus is ‘Highly Adapted’ for Human (Not Bat or Pangolin) Infection – READ

2020

September 3, 2020 – SciMex Press Release: Computer models for 80 potential COVID-19 treatments – READ

  • Australian scientists using cloud-based supercomputer programs have joined forces with biotechnology company Vaxine Pty Ltd to identify up to 80 new potential candidate drugs against the COVID-19 virus.
  • The Australian Government today announced a $1 million grant to support the Covax-19® vaccination’s progress through clinical trials. The grant, matched by Vaxine, is one of 13 early stage biomedical projects to receive funding through the Federal Government’s Biomedical Translation Bridge (BTB) program, part of Australia’s landmark Medical Research Future Fund.

September 1, 2020 – ArXiv journal pre print: Computational screening of repurposed drugs and natural products against SARS-Cov-2 main protease (Mpro) as potential COVID-19 therapies – Petrovsky et al – READ

July 31, 2020 – SciMex Press Release: EXPERT REACTION: South Australian COVID-19 vaccine trial clears phase 1 – READ Prof Paul Griffin who is involved with Novavax and UQ responds to nothing being published as yet-

  • “A word of caution, however, in that no data has been shared, much less published in a peer-reviewed journal, which is really what is required to substantiate any claims of safety or efficacy. This should hopefully follow in the near future. It was also a rather small phase 1 study and, when talking about immune responses, only an antibody response has thus far been mentioned. And only systemic side-effects have been mentioned as not being present” Prof Griffin
    • [I note that both COVID-19 mRNA vaccines were heralded “safe and effective” following simple press releases, some claims were based on an antibody response in just 8 mice!!]

June 30, 2020 – ClinicalTrials.gov: Monovalent Recombinant COVID19 Vaccine (COVAX19) – trial #NCT04453852, sponsored by Vaxine Pty Ltd – READ

  • Covax-19 consists of highly purified recombinant SARS-COV-2 spike protein plus Advax-SM adjuvant in a sterile solution for intramuscular injection. COVAX-19™ vaccine is manufactured using a Sf9 platform. Advax-CpG adjuvant has previously been well tolerated and effective in trials of hepatitis B, H5N1 (NCT02335164) and H7N9 (NCT03038776) influenza vaccines and has recently been tested by the NIH in a US multicentre clinical trial with 2 quadrivalent seasonal influenza vaccines (NCT03945825).”

May 14, 2020 – SciMex Press Release: Origins of COVID-19 still a mystery by Petrovsky – READ

  • ArXiv Preprint: In silico comparison of spike protein-ACE2 binding affinities across species; significance for the possible origin of the SARS-CoV-2 virus by Petrovsky et al – READ Published Nov 21, 2020

April 3, 2020 – Scimex | Press Release: Closing in on COVID-19 vaccine – READ, ARCHIVE

  • “South Australian researchers working with Oracle Cloud technology and vaccine technology developed by local company Vaxine Pty Ltd are testing a vaccine candidate against the SARS-CoV-2 coronavirus responsible for the COVID-19 pandemic. The team is headed by Nikolai Petrovsky, Flinders University Professor and Research Director at Vaxine”
  • The vaccine has progressed into animal testing in the US and, once we confirm it is safe and effective, will then be advanced into human trials,” says Professor Petrovsky – stressing expectations shouldn’t be elevated until all testing is completed.
  • “The latest cloud-based technology provided by Oracle enabled the team to “dramatically speed up our ability to analyse the COVID-19 virus and use this information to design the vaccine candidate”.”
  • “As soon as the genomic sequence of COVID-19 became available in January, we immediately used this, combined with our previous experience in developing a SARS coronavirus vaccine, to characterise the key viral attachment molecule called the spike protein,”
  • We used computer models of the spike protein and its human receptor, ACE2, to identify how the virus was infecting human cells, and then were able to design a vaccine to block this process,”
  • The team has exploited the very latest technologies, including AI, advanced manufacturing and Cloud computing to accelerate vaccine design, shaving years off normal development timeframes,” says Flinders University Associate Professor Dimitar Sajkov, a respiratory physician in South Australia
  • We achieved great results with Vaxine’s swine flu vaccine developed during the 2009 swine flu pandemic, where we commenced clinical trials of a vaccine within 3 months of discovery of the virus. We hope to achieve similar results with their COVID-19 vaccine candidate when it is ready for human testing” he says.

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